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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
METTL6
All Species:
36.97
Human Site:
Y176
Identified Species:
73.94
UniProt:
Q8TCB7
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8TCB7
NP_689609.2
284
33251
Y176
H
L
V
L
Q
N
I
Y
K
V
L
K
P
G
K
Chimpanzee
Pan troglodytes
XP_001159583
284
33188
Y176
H
L
V
L
Q
N
I
Y
K
V
L
K
P
G
K
Rhesus Macaque
Macaca mulatta
XP_001082383
284
33277
Y176
H
L
V
L
E
N
I
Y
K
V
L
K
P
G
K
Dog
Lupus familis
XP_534257
274
32152
Y175
H
L
V
L
Q
N
I
Y
Q
V
L
K
P
G
K
Cat
Felis silvestris
Mouse
Mus musculus
Q8BVH9
282
32768
Y176
R
L
V
L
L
N
V
Y
K
V
L
K
P
G
R
Rat
Rattus norvegicus
Q6AXU8
287
33363
Y176
H
L
V
L
L
N
V
Y
K
V
L
K
P
G
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514519
297
34555
Y200
H
L
A
L
Q
N
I
Y
K
V
L
K
P
G
K
Chicken
Gallus gallus
Q5ZHP8
370
42711
S272
Q
C
V
I
N
K
L
S
R
L
L
K
P
G
G
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
A8KBL7
353
40469
G256
Q
K
S
I
N
R
L
G
R
L
L
K
P
G
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q86BS6
325
38113
Y231
Q
R
V
L
D
N
C
Y
R
Y
L
R
P
G
G
Honey Bee
Apis mellifera
XP_623532
439
50081
Y179
R
K
V
V
E
N
L
Y
N
V
L
D
K
G
G
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_794407
277
31720
Y179
L
Q
S
I
Q
N
I
Y
K
A
L
C
P
G
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.3
94.3
89.7
N.A.
85.5
84.3
N.A.
77.7
37
N.A.
36.8
N.A.
38.1
32.3
N.A.
59.5
Protein Similarity:
100
99.6
97.1
94
N.A.
91.9
90.9
N.A.
85.1
49.7
N.A.
50.4
N.A.
51.3
46.4
N.A.
73.2
P-Site Identity:
100
100
93.3
93.3
N.A.
73.3
80
N.A.
93.3
33.3
N.A.
26.6
N.A.
46.6
40
N.A.
53.3
P-Site Similarity:
100
100
100
100
N.A.
86.6
93.3
N.A.
93.3
60
N.A.
53.3
N.A.
60
60
N.A.
60
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
9
0
0
0
0
0
0
9
0
0
0
0
0
% A
% Cys:
0
9
0
0
0
0
9
0
0
0
0
9
0
0
0
% C
% Asp:
0
0
0
0
9
0
0
0
0
0
0
9
0
0
0
% D
% Glu:
0
0
0
0
17
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
9
0
0
0
0
0
100
42
% G
% His:
50
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
25
0
0
50
0
0
0
0
0
0
0
0
% I
% Lys:
0
17
0
0
0
9
0
0
59
0
0
75
9
0
42
% K
% Leu:
9
59
0
67
17
0
25
0
0
17
100
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
17
84
0
0
9
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
92
0
0
% P
% Gln:
25
9
0
0
42
0
0
0
9
0
0
0
0
0
0
% Q
% Arg:
17
9
0
0
0
9
0
0
25
0
0
9
0
0
17
% R
% Ser:
0
0
17
0
0
0
0
9
0
0
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
75
9
0
0
17
0
0
67
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
84
0
9
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _