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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
METTL6
All Species:
42.12
Human Site:
Y190
Identified Species:
84.24
UniProt:
Q8TCB7
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8TCB7
NP_689609.2
284
33251
Y190
K
S
V
L
F
R
D
Y
G
L
Y
D
H
A
M
Chimpanzee
Pan troglodytes
XP_001159583
284
33188
Y190
K
S
V
L
F
R
D
Y
G
L
Y
D
H
A
M
Rhesus Macaque
Macaca mulatta
XP_001082383
284
33277
Y190
K
S
V
L
F
R
D
Y
G
L
Y
D
H
A
M
Dog
Lupus familis
XP_534257
274
32152
Y189
K
S
V
L
F
R
D
Y
G
L
Y
D
H
A
M
Cat
Felis silvestris
Mouse
Mus musculus
Q8BVH9
282
32768
Y190
R
S
V
L
F
R
D
Y
G
L
N
D
H
A
M
Rat
Rattus norvegicus
Q6AXU8
287
33363
Y190
R
S
V
L
F
R
D
Y
G
L
N
D
H
A
M
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514519
297
34555
Y214
K
C
V
L
F
R
D
Y
G
L
Y
D
H
A
M
Chicken
Gallus gallus
Q5ZHP8
370
42711
Y286
G
M
I
L
L
R
D
Y
G
R
Y
D
L
A
Q
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
A8KBL7
353
40469
Y270
G
V
L
L
L
R
D
Y
G
R
Y
D
M
A
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q86BS6
325
38113
Y245
G
L
L
L
F
R
D
Y
G
R
Y
D
L
A
Q
Honey Bee
Apis mellifera
XP_623532
439
50081
Y193
G
I
V
L
F
R
D
Y
G
L
Y
D
M
A
Q
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_794407
277
31720
Y193
G
L
V
L
F
R
D
Y
G
L
H
D
H
A
M
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.3
94.3
89.7
N.A.
85.5
84.3
N.A.
77.7
37
N.A.
36.8
N.A.
38.1
32.3
N.A.
59.5
Protein Similarity:
100
99.6
97.1
94
N.A.
91.9
90.9
N.A.
85.1
49.7
N.A.
50.4
N.A.
51.3
46.4
N.A.
73.2
P-Site Identity:
100
100
100
100
N.A.
86.6
86.6
N.A.
93.3
53.3
N.A.
53.3
N.A.
60
73.3
N.A.
80
P-Site Similarity:
100
100
100
100
N.A.
93.3
93.3
N.A.
93.3
60
N.A.
60
N.A.
66.6
73.3
N.A.
86.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
0
100
0
% A
% Cys:
0
9
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
100
0
0
0
0
100
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
84
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
42
0
0
0
0
0
0
0
100
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
9
0
67
0
0
% H
% Ile:
0
9
9
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
42
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
17
17
100
17
0
0
0
0
75
0
0
17
0
0
% L
% Met:
0
9
0
0
0
0
0
0
0
0
0
0
17
0
67
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
17
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
34
% Q
% Arg:
17
0
0
0
0
100
0
0
0
25
0
0
0
0
0
% R
% Ser:
0
50
0
0
0
0
0
0
0
0
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
9
75
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
100
0
0
75
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _