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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SLC22A8
All Species:
28.48
Human Site:
S259
Identified Species:
69.63
UniProt:
Q8TCC7
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8TCC7
NP_004245.2
542
59856
S259
S
S
W
W
T
P
E
S
I
R
W
L
V
L
S
Chimpanzee
Pan troglodytes
XP_508510
554
60979
S259
S
S
W
W
T
P
E
S
I
R
W
L
V
L
S
Rhesus Macaque
Macaca mulatta
XP_001115844
542
59751
S259
S
S
W
W
T
P
E
S
I
R
W
L
V
L
T
Dog
Lupus familis
XP_533257
531
58120
S245
A
A
F
S
P
S
L
S
V
Y
M
V
F
R
F
Cat
Felis silvestris
Mouse
Mus musculus
O88909
537
59228
S259
L
S
W
W
V
P
E
S
I
R
W
L
V
L
S
Rat
Rattus norvegicus
Q9R1U7
536
59168
S259
L
S
W
W
V
P
E
S
I
R
W
L
V
L
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001521678
391
43458
G121
V
R
W
L
V
L
K
G
K
P
E
K
A
L
W
Chicken
Gallus gallus
Frog
Xenopus laevis
Q66J52
552
61646
S273
Y
S
W
W
I
P
E
S
G
R
W
L
V
L
S
Zebra Danio
Brachydanio rerio
Q6NYN7
560
61953
S279
Y
S
W
W
F
L
E
S
A
R
W
L
V
L
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VCA2
548
60985
S267
Y
Y
W
I
I
P
E
S
A
R
W
L
L
M
K
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
93.1
96.3
63
N.A.
77.4
78.9
N.A.
48.3
N.A.
52.1
48.2
N.A.
32.6
N.A.
N.A.
N.A.
Protein Similarity:
100
94
98.5
72.3
N.A.
86.9
88.7
N.A.
57.3
N.A.
69.9
66.4
N.A.
53.6
N.A.
N.A.
N.A.
P-Site Identity:
100
100
93.3
6.6
N.A.
86.6
86.6
N.A.
13.3
N.A.
80
66.6
N.A.
46.6
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
40
N.A.
86.6
86.6
N.A.
20
N.A.
80
73.3
N.A.
60
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
10
0
0
0
0
0
0
20
0
0
0
10
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
80
0
0
0
10
0
0
0
0
% E
% Phe:
0
0
10
0
10
0
0
0
0
0
0
0
10
0
10
% F
% Gly:
0
0
0
0
0
0
0
10
10
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
10
20
0
0
0
50
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
10
0
10
0
0
10
0
0
10
% K
% Leu:
20
0
0
10
0
20
10
0
0
0
0
80
10
80
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
10
0
0
10
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
10
70
0
0
0
10
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
10
0
0
0
0
0
0
0
80
0
0
0
10
0
% R
% Ser:
30
70
0
10
0
10
0
90
0
0
0
0
0
0
50
% S
% Thr:
0
0
0
0
30
0
0
0
0
0
0
0
0
0
20
% T
% Val:
10
0
0
0
30
0
0
0
10
0
0
10
70
0
0
% V
% Trp:
0
0
90
70
0
0
0
0
0
0
80
0
0
0
10
% W
% Tyr:
30
10
0
0
0
0
0
0
0
10
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _