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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FAM45A
All Species:
17.88
Human Site:
T175
Identified Species:
39.33
UniProt:
Q8TCE6
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8TCE6
NP_996892.1
357
40513
T175
M
E
T
V
I
L
H
T
A
L
M
L
K
K
R
Chimpanzee
Pan troglodytes
XP_521351
433
49072
T214
M
E
T
V
I
L
H
T
A
L
M
L
K
K
R
Rhesus Macaque
Macaca mulatta
XP_001102570
260
29451
G99
I
C
Q
S
E
E
N
G
S
F
L
S
K
D
F
Dog
Lupus familis
XP_535029
343
39243
K175
R
I
V
V
Y
H
P
K
I
E
A
V
Q
E
F
Cat
Felis silvestris
Mouse
Mus musculus
Q9D8N2
357
40402
T175
M
E
T
V
I
L
H
T
A
L
M
L
K
K
R
Rat
Rattus norvegicus
NP_001121153
235
26480
Q73
H
P
K
I
E
A
V
Q
E
F
T
R
T
L
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514659
549
61761
T367
M
E
T
V
I
L
Y
T
A
V
M
L
K
K
R
Chicken
Gallus gallus
NP_001026410
216
24632
T55
D
E
S
K
L
L
H
T
F
V
F
G
Q
Y
K
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_684048
190
21445
S29
C
Q
S
D
E
N
G
S
F
L
I
K
D
Y
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_001120151
352
40366
I179
L
L
L
K
K
R
I
I
V
Y
H
H
S
L
E
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_782995
349
39118
V179
L
L
L
K
K
K
I
V
V
Y
H
S
R
V
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
69.5
63.5
89.9
N.A.
90.4
58.8
N.A.
53.3
53.2
N.A.
39.7
N.A.
N.A.
38.3
N.A.
50.9
Protein Similarity:
100
73.6
66.9
93
N.A.
96.6
63.3
N.A.
60.4
57.7
N.A.
47.6
N.A.
N.A.
63.3
N.A.
72.5
P-Site Identity:
100
100
6.6
6.6
N.A.
100
0
N.A.
86.6
26.6
N.A.
6.6
N.A.
N.A.
0
N.A.
0
P-Site Similarity:
100
100
33.3
26.6
N.A.
100
6.6
N.A.
100
60
N.A.
33.3
N.A.
N.A.
6.6
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
10
0
0
37
0
10
0
0
0
0
% A
% Cys:
10
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
10
0
0
10
0
0
0
0
0
0
0
0
10
10
10
% D
% Glu:
0
46
0
0
28
10
0
0
10
10
0
0
0
10
19
% E
% Phe:
0
0
0
0
0
0
0
0
19
19
10
0
0
0
19
% F
% Gly:
0
0
0
0
0
0
10
10
0
0
0
10
0
0
0
% G
% His:
10
0
0
0
0
10
37
0
0
0
19
10
0
0
0
% H
% Ile:
10
10
0
10
37
0
19
10
10
0
10
0
0
0
0
% I
% Lys:
0
0
10
28
19
10
0
10
0
0
0
10
46
37
10
% K
% Leu:
19
19
19
0
10
46
0
0
0
37
10
37
0
19
0
% L
% Met:
37
0
0
0
0
0
0
0
0
0
37
0
0
0
0
% M
% Asn:
0
0
0
0
0
10
10
0
0
0
0
0
0
0
0
% N
% Pro:
0
10
0
0
0
0
10
0
0
0
0
0
0
0
10
% P
% Gln:
0
10
10
0
0
0
0
10
0
0
0
0
19
0
0
% Q
% Arg:
10
0
0
0
0
10
0
0
0
0
0
10
10
0
37
% R
% Ser:
0
0
19
10
0
0
0
10
10
0
0
19
10
0
0
% S
% Thr:
0
0
37
0
0
0
0
46
0
0
10
0
10
0
0
% T
% Val:
0
0
10
46
0
0
10
10
19
19
0
10
0
10
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
10
0
10
0
0
19
0
0
0
19
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _