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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: KIAA1524 All Species: 35.15
Human Site: T454 Identified Species: 70.3
UniProt: Q8TCG1 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8TCG1 NP_065941.2 905 102185 T454 T L I E Q Q F T Y G K I D L G
Chimpanzee Pan troglodytes XP_001151616 906 102287 T454 T L I E Q Q F T Y G K I D L G
Rhesus Macaque Macaca mulatta XP_001101310 906 102265 T454 T L I E Q Q F T Y G K I D L G
Dog Lupus familis XP_535731 908 102554 T456 T L I E Q Q F T Y G K I D L G
Cat Felis silvestris
Mouse Mus musculus Q8BWY9 907 102093 T455 T L I E Q Q F T Y G K I D L G
Rat Rattus norvegicus XP_340983 909 102425 T457 M L I E Q Q F T Y G K I D L G
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001509209 959 107012 T507 S L I E Q Q F T W R G I E F A
Chicken Gallus gallus Q5ZMJ7 909 101741 S459 S L I E H Q F S Y S G I D A G
Frog Xenopus laevis Q5XK92 906 101650 S459 S M V D Y Q F S C S G V D T S
Zebra Danio Brachydanio rerio NP_001107893 896 99448 S459 S Q V E L L L S Y S Q D L T G
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_796563 928 104857 T483 Q V G I S K T T R M A V G D C
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P25386 1790 206434 H938 N L S K E K E H I S K E L V E
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.4 98.7 90.9 N.A. 87.2 87.3 N.A. 65.9 69.9 65.8 51.3 N.A. N.A. N.A. N.A. 39
Protein Similarity: 100 99.4 99.4 95.1 N.A. 92.9 93 N.A. 80.2 83.6 80.1 71.1 N.A. N.A. N.A. N.A. 59.4
P-Site Identity: 100 100 100 100 N.A. 100 93.3 N.A. 53.3 60 20 20 N.A. N.A. N.A. N.A. 6.6
P-Site Similarity: 100 100 100 100 N.A. 100 93.3 N.A. 73.3 73.3 60 46.6 N.A. N.A. N.A. N.A. 26.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. 20.4 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 34.6 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 13.3 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 40 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 0 0 9 0 0 9 9 % A
% Cys: 0 0 0 0 0 0 0 0 9 0 0 0 0 0 9 % C
% Asp: 0 0 0 9 0 0 0 0 0 0 0 9 67 9 0 % D
% Glu: 0 0 0 75 9 0 9 0 0 0 0 9 9 0 9 % E
% Phe: 0 0 0 0 0 0 75 0 0 0 0 0 0 9 0 % F
% Gly: 0 0 9 0 0 0 0 0 0 50 25 0 9 0 67 % G
% His: 0 0 0 0 9 0 0 9 0 0 0 0 0 0 0 % H
% Ile: 0 0 67 9 0 0 0 0 9 0 0 67 0 0 0 % I
% Lys: 0 0 0 9 0 17 0 0 0 0 59 0 0 0 0 % K
% Leu: 0 75 0 0 9 9 9 0 0 0 0 0 17 50 0 % L
% Met: 9 9 0 0 0 0 0 0 0 9 0 0 0 0 0 % M
% Asn: 9 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 9 9 0 0 59 75 0 0 0 0 9 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 9 9 0 0 0 0 0 % R
% Ser: 34 0 9 0 9 0 0 25 0 34 0 0 0 0 9 % S
% Thr: 42 0 0 0 0 0 9 67 0 0 0 0 0 17 0 % T
% Val: 0 9 17 0 0 0 0 0 0 0 0 17 0 9 0 % V
% Trp: 0 0 0 0 0 0 0 0 9 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 9 0 0 0 67 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _