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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PI4K2B All Species: 5.76
Human Site: S17 Identified Species: 10.56
UniProt: Q8TCG2 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8TCG2 NP_060793.2 481 54744 S17 L A S A D G G S P E E E E D G
Chimpanzee Pan troglodytes XP_001164880 481 54254 D17 P E R A Q P P D Y T F P S G S
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_543953 484 54388 S26 T F P S C S G S H F P Q V P G
Cat Felis silvestris
Mouse Mus musculus Q8CBQ5 469 53459 E17 P S E D E D E E R E P L L P R
Rat Rattus norvegicus Q5XIL2 477 54446 R17 A E A C E A T R P S E D E D E
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001513782 411 46894 F18 E S G Q P A L F V L G T A E M
Chicken Gallus gallus Q5ZIK0 479 53903 E17 E Q L L L L S E P A L H A G P
Frog Xenopus laevis Q6DCQ8 495 56331 A22 L L V L L D P A A E Q L E V S
Zebra Danio Brachydanio rerio Q49GP5 501 56180 T20 G N G S G D S T P E T N F L S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_001120474 466 53705 S25 S Q N N T N T S V L V E T D A
Nematode Worm Caenorhab. elegans NP_508849 593 66195 S28 R M S S S G A S E S E V E T C
Sea Urchin Strong. purpuratus XP_801707 506 57844 K35 S D S R N N G K L L D L E S S
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P42951 607 70198 Q27 V N S Y D W L Q F R D E Q D H
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 58.6 N.A. 58.8 N.A. 79.2 79.8 N.A. 71.7 70.6 70.7 67.4 N.A. N.A. 54.6 40.2 53.7
Protein Similarity: 100 71.9 N.A. 71.4 N.A. 87.5 87.5 N.A. 77.7 78.3 78.7 78.2 N.A. N.A. 70.2 53.6 66.2
P-Site Identity: 100 6.6 N.A. 20 N.A. 6.6 26.6 N.A. 0 6.6 20 13.3 N.A. N.A. 20 33.3 20
P-Site Similarity: 100 6.6 N.A. 33.3 N.A. 20 46.6 N.A. 13.3 6.6 33.3 26.6 N.A. N.A. 26.6 40 33.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. 26.1 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 42.6 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 26.6 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 46.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 8 8 16 0 16 8 8 8 8 0 0 16 0 8 % A
% Cys: 0 0 0 8 8 0 0 0 0 0 0 0 0 0 8 % C
% Asp: 0 8 0 8 16 24 0 8 0 0 16 8 0 31 0 % D
% Glu: 16 16 8 0 16 0 8 16 8 31 24 24 39 8 8 % E
% Phe: 0 8 0 0 0 0 0 8 8 8 8 0 8 0 0 % F
% Gly: 8 0 16 0 8 16 24 0 0 0 8 0 0 16 16 % G
% His: 0 0 0 0 0 0 0 0 8 0 0 8 0 0 8 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 8 0 0 0 0 0 0 0 % K
% Leu: 16 8 8 16 16 8 16 0 8 24 8 24 8 8 0 % L
% Met: 0 8 0 0 0 0 0 0 0 0 0 0 0 0 8 % M
% Asn: 0 16 8 8 8 16 0 0 0 0 0 8 0 0 0 % N
% Pro: 16 0 8 0 8 8 16 0 31 0 16 8 0 16 8 % P
% Gln: 0 16 0 8 8 0 0 8 0 0 8 8 8 0 0 % Q
% Arg: 8 0 8 8 0 0 0 8 8 8 0 0 0 0 8 % R
% Ser: 16 16 31 24 8 8 16 31 0 16 0 0 8 8 31 % S
% Thr: 8 0 0 0 8 0 16 8 0 8 8 8 8 8 0 % T
% Val: 8 0 8 0 0 0 0 0 16 0 8 8 8 8 0 % V
% Trp: 0 0 0 0 0 8 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 8 0 0 0 0 8 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _