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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PI4K2B
All Species:
37.27
Human Site:
S375
Identified Species:
68.33
UniProt:
Q8TCG2
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8TCG2
NP_060793.2
481
54744
S375
P
Q
A
K
V
P
F
S
E
E
I
R
N
L
I
Chimpanzee
Pan troglodytes
XP_001164880
481
54254
K375
W
A
W
L
P
Q
A
K
V
P
F
S
Q
E
I
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_543953
484
54388
K378
W
A
W
L
P
Q
A
K
V
P
F
S
Q
E
I
Cat
Felis silvestris
Mouse
Mus musculus
Q8CBQ5
469
53459
S363
P
Q
A
K
V
P
F
S
E
E
T
R
N
L
I
Rat
Rattus norvegicus
Q5XIL2
477
54446
S371
P
Q
A
K
V
P
F
S
E
E
T
R
N
L
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513782
411
46894
S303
S
Q
A
K
V
P
F
S
E
E
T
R
D
L
I
Chicken
Gallus gallus
Q5ZIK0
479
53903
S373
S
Q
A
Q
V
P
F
S
Q
E
T
R
D
L
V
Frog
Xenopus laevis
Q6DCQ8
495
56331
S389
P
Q
A
K
V
P
F
S
Q
E
T
R
D
L
I
Zebra Danio
Brachydanio rerio
Q49GP5
501
56180
S395
P
Q
A
K
V
A
F
S
Q
E
T
R
D
L
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_001120474
466
53705
S360
S
Q
A
K
Q
P
F
S
D
V
T
R
E
L
V
Nematode Worm
Caenorhab. elegans
NP_508849
593
66195
S427
P
Q
A
Q
I
P
F
S
D
D
I
V
D
L
L
Sea Urchin
Strong. purpuratus
XP_801707
506
57844
S397
P
Q
A
K
Q
K
F
S
K
E
T
I
D
H
V
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P42951
607
70198
S446
Q
L
L
A
K
P
F
S
E
Q
M
R
S
H
F
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
58.6
N.A.
58.8
N.A.
79.2
79.8
N.A.
71.7
70.6
70.7
67.4
N.A.
N.A.
54.6
40.2
53.7
Protein Similarity:
100
71.9
N.A.
71.4
N.A.
87.5
87.5
N.A.
77.7
78.3
78.7
78.2
N.A.
N.A.
70.2
53.6
66.2
P-Site Identity:
100
6.6
N.A.
6.6
N.A.
93.3
93.3
N.A.
80
60
80
66.6
N.A.
N.A.
53.3
53.3
46.6
P-Site Similarity:
100
6.6
N.A.
6.6
N.A.
93.3
93.3
N.A.
86.6
86.6
93.3
86.6
N.A.
N.A.
66.6
93.3
66.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
26.1
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
42.6
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
33.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
53.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
16
77
8
0
8
16
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
16
8
0
0
47
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
39
62
0
0
8
16
0
% E
% Phe:
0
0
0
0
0
0
85
0
0
0
16
0
0
0
8
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
16
0
% H
% Ile:
0
0
0
0
8
0
0
0
0
0
16
8
0
0
54
% I
% Lys:
0
0
0
62
8
8
0
16
8
0
0
0
0
0
0
% K
% Leu:
0
8
8
16
0
0
0
0
0
0
0
0
0
70
8
% L
% Met:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
24
0
0
% N
% Pro:
54
0
0
0
16
70
0
0
0
16
0
0
0
0
0
% P
% Gln:
8
77
0
16
16
16
0
0
24
8
0
0
16
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
70
0
0
0
% R
% Ser:
24
0
0
0
0
0
0
85
0
0
0
16
8
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
62
0
0
0
0
% T
% Val:
0
0
0
0
54
0
0
0
16
8
0
8
0
0
31
% V
% Trp:
16
0
16
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _