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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PI4K2B
All Species:
32.42
Human Site:
S437
Identified Species:
59.44
UniProt:
Q8TCG2
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8TCG2
NP_060793.2
481
54744
S437
Q
A
L
R
D
G
K
S
P
F
Q
L
V
Q
I
Chimpanzee
Pan troglodytes
XP_001164880
481
54254
K437
L
N
L
T
Q
A
L
K
D
N
K
S
P
L
H
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_543953
484
54388
K440
L
N
L
T
Q
A
L
K
D
N
K
S
P
L
H
Cat
Felis silvestris
Mouse
Mus musculus
Q8CBQ5
469
53459
S425
Q
A
L
R
D
G
K
S
P
M
Q
L
A
Q
M
Rat
Rattus norvegicus
Q5XIL2
477
54446
S433
Q
A
L
R
D
G
K
S
P
M
Q
L
A
Q
M
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513782
411
46894
S365
Q
A
L
K
D
G
K
S
P
I
Q
L
V
Q
M
Chicken
Gallus gallus
Q5ZIK0
479
53903
S435
Q
A
L
K
D
G
K
S
P
I
Q
L
V
Q
M
Frog
Xenopus laevis
Q6DCQ8
495
56331
T451
Q
A
L
K
D
G
K
T
P
I
Q
L
V
Q
M
Zebra Danio
Brachydanio rerio
Q49GP5
501
56180
S457
Q
A
L
K
D
G
K
S
P
I
Q
L
V
Q
M
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_001120474
466
53705
S422
Q
A
L
K
D
A
K
S
P
V
Q
L
V
Q
M
Nematode Worm
Caenorhab. elegans
NP_508849
593
66195
S489
E
A
L
M
K
K
K
S
P
Y
Q
L
I
Q
M
Sea Urchin
Strong. purpuratus
XP_801707
506
57844
A459
Q
A
M
R
D
N
K
A
P
V
Q
L
V
Q
M
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P42951
607
70198
Q508
E
T
L
K
D
P
R
Q
G
P
L
E
L
V
R
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
58.6
N.A.
58.8
N.A.
79.2
79.8
N.A.
71.7
70.6
70.7
67.4
N.A.
N.A.
54.6
40.2
53.7
Protein Similarity:
100
71.9
N.A.
71.4
N.A.
87.5
87.5
N.A.
77.7
78.3
78.7
78.2
N.A.
N.A.
70.2
53.6
66.2
P-Site Identity:
100
6.6
N.A.
6.6
N.A.
80
80
N.A.
80
80
73.3
80
N.A.
N.A.
73.3
53.3
66.6
P-Site Similarity:
100
13.3
N.A.
13.3
N.A.
86.6
86.6
N.A.
93.3
93.3
93.3
93.3
N.A.
N.A.
86.6
80
86.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
26.1
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
42.6
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
40
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
77
0
0
0
24
0
8
0
0
0
0
16
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
77
0
0
0
16
0
0
0
0
0
0
% D
% Glu:
16
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
54
0
0
8
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
16
% H
% Ile:
0
0
0
0
0
0
0
0
0
31
0
0
8
0
8
% I
% Lys:
0
0
0
47
8
8
77
16
0
0
16
0
0
0
0
% K
% Leu:
16
0
93
0
0
0
16
0
0
0
8
77
8
16
0
% L
% Met:
0
0
8
8
0
0
0
0
0
16
0
0
0
0
70
% M
% Asn:
0
16
0
0
0
8
0
0
0
16
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
8
0
0
77
8
0
0
16
0
0
% P
% Gln:
70
0
0
0
16
0
0
8
0
0
77
0
0
77
0
% Q
% Arg:
0
0
0
31
0
0
8
0
0
0
0
0
0
0
8
% R
% Ser:
0
0
0
0
0
0
0
62
0
0
0
16
0
0
0
% S
% Thr:
0
8
0
16
0
0
0
8
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
16
0
0
54
8
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _