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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PI4K2B
All Species:
9.39
Human Site:
S45
Identified Species:
17.22
UniProt:
Q8TCG2
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8TCG2
NP_060793.2
481
54744
S45
P
R
R
G
A
P
G
S
A
V
R
L
L
D
A
Chimpanzee
Pan troglodytes
XP_001164880
481
54254
G34
H
F
P
Q
V
P
G
G
A
V
R
V
A
A
A
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_543953
484
54388
A43
V
R
V
A
A
A
A
A
A
A
A
A
G
P
A
Cat
Felis silvestris
Mouse
Mus musculus
Q8CBQ5
469
53459
S37
P
R
R
V
A
P
G
S
A
V
R
M
Q
A
D
Rat
Rattus norvegicus
Q5XIL2
477
54446
S45
P
R
R
G
A
P
G
S
A
V
R
L
Q
A
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513782
411
46894
F34
I
F
L
E
D
P
E
F
A
E
I
I
L
R
A
Chicken
Gallus gallus
Q5ZIK0
479
53903
G33
A
G
R
A
A
P
G
G
A
V
R
L
R
G
E
Frog
Xenopus laevis
Q6DCQ8
495
56331
S48
S
A
R
A
A
P
G
S
A
V
R
F
F
C
D
Zebra Danio
Brachydanio rerio
Q49GP5
501
56180
A52
G
L
S
L
N
P
G
A
A
V
R
I
S
D
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_001120474
466
53705
N42
D
L
S
I
T
S
N
N
C
L
P
I
N
D
C
Nematode Worm
Caenorhab. elegans
NP_508849
593
66195
K47
G
L
L
G
S
R
G
K
K
V
K
H
E
R
S
Sea Urchin
Strong. purpuratus
XP_801707
506
57844
N73
P
D
V
I
F
E
P
N
T
A
T
L
D
N
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P42951
607
70198
Q53
P
G
V
G
S
N
A
Q
N
S
D
I
A
E
A
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
58.6
N.A.
58.8
N.A.
79.2
79.8
N.A.
71.7
70.6
70.7
67.4
N.A.
N.A.
54.6
40.2
53.7
Protein Similarity:
100
71.9
N.A.
71.4
N.A.
87.5
87.5
N.A.
77.7
78.3
78.7
78.2
N.A.
N.A.
70.2
53.6
66.2
P-Site Identity:
100
40
N.A.
26.6
N.A.
66.6
80
N.A.
26.6
53.3
53.3
40
N.A.
N.A.
6.6
20
13.3
P-Site Similarity:
100
46.6
N.A.
33.3
N.A.
73.3
80
N.A.
33.3
53.3
53.3
60
N.A.
N.A.
26.6
40
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
26.1
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
42.6
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
20
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
40
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
8
0
24
47
8
16
16
70
16
8
8
16
24
39
% A
% Cys:
0
0
0
0
0
0
0
0
8
0
0
0
0
8
8
% C
% Asp:
8
8
0
0
8
0
0
0
0
0
8
0
8
24
24
% D
% Glu:
0
0
0
8
0
8
8
0
0
8
0
0
8
8
8
% E
% Phe:
0
16
0
0
8
0
0
8
0
0
0
8
8
0
0
% F
% Gly:
16
16
0
31
0
0
62
16
0
0
0
0
8
8
0
% G
% His:
8
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% H
% Ile:
8
0
0
16
0
0
0
0
0
0
8
31
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
8
8
0
8
0
0
0
0
% K
% Leu:
0
24
16
8
0
0
0
0
0
8
0
31
16
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% M
% Asn:
0
0
0
0
8
8
8
16
8
0
0
0
8
8
0
% N
% Pro:
39
0
8
0
0
62
8
0
0
0
8
0
0
8
0
% P
% Gln:
0
0
0
8
0
0
0
8
0
0
0
0
16
0
0
% Q
% Arg:
0
31
39
0
0
8
0
0
0
0
54
0
8
16
0
% R
% Ser:
8
0
16
0
16
8
0
31
0
8
0
0
8
0
24
% S
% Thr:
0
0
0
0
8
0
0
0
8
0
8
0
0
0
0
% T
% Val:
8
0
24
8
8
0
0
0
0
62
0
8
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _