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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PI4K2B
All Species:
5.76
Human Site:
S74
Identified Species:
10.56
UniProt:
Q8TCG2
Number Species:
12
Phosphosite Substitution
Charge Score:
0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8TCG2
NP_060793.2
481
54744
S74
P
P
G
D
V
G
V
S
R
S
S
S
A
E
L
Chimpanzee
Pan troglodytes
XP_001164880
481
54254
D55
P
P
G
S
P
G
H
D
R
E
R
Q
P
L
L
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_543953
484
54388
D60
P
P
G
S
P
G
H
D
R
E
R
Q
P
L
L
Cat
Felis silvestris
Mouse
Mus musculus
Q8CBQ5
469
53459
S68
V
S
G
E
G
S
I
S
A
S
L
S
T
E
L
Rat
Rattus norvegicus
Q5XIL2
477
54446
S76
V
S
E
D
R
S
I
S
A
S
L
S
T
E
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513782
411
46894
F50
Q
A
I
D
G
G
V
F
P
E
R
I
S
Q
G
Chicken
Gallus gallus
Q5ZIK0
479
53903
R72
L
R
A
S
G
R
G
R
R
A
G
A
A
R
D
Frog
Xenopus laevis
Q6DCQ8
495
56331
R81
P
M
S
P
R
A
V
R
K
G
R
T
R
L
S
Zebra Danio
Brachydanio rerio
Q49GP5
501
56180
L86
L
P
G
P
A
G
S
L
S
P
R
A
G
K
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_001120474
466
53705
E65
F
V
P
N
L
S
N
E
Q
T
I
A
I
D
S
Nematode Worm
Caenorhab. elegans
NP_508849
593
66195
L94
P
Y
T
S
D
D
E
L
L
H
T
G
S
D
A
Sea Urchin
Strong. purpuratus
XP_801707
506
57844
S89
T
S
S
P
A
G
H
S
R
Q
E
T
E
N
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P42951
607
70198
E77
S
L
V
N
V
P
S
E
S
P
R
P
D
Q
T
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
58.6
N.A.
58.8
N.A.
79.2
79.8
N.A.
71.7
70.6
70.7
67.4
N.A.
N.A.
54.6
40.2
53.7
Protein Similarity:
100
71.9
N.A.
71.4
N.A.
87.5
87.5
N.A.
77.7
78.3
78.7
78.2
N.A.
N.A.
70.2
53.6
66.2
P-Site Identity:
100
40
N.A.
40
N.A.
40
40
N.A.
20
13.3
13.3
20
N.A.
N.A.
0
6.6
20
P-Site Similarity:
100
40
N.A.
40
N.A.
53.3
46.6
N.A.
33.3
26.6
26.6
33.3
N.A.
N.A.
40
26.6
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
26.1
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
42.6
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
8
0
16
8
0
0
16
8
0
24
16
0
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
24
8
8
0
16
0
0
0
0
8
16
8
% D
% Glu:
0
0
8
8
0
0
8
16
0
24
8
0
8
24
16
% E
% Phe:
8
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% F
% Gly:
0
0
39
0
24
47
8
0
0
8
8
8
8
0
8
% G
% His:
0
0
0
0
0
0
24
0
0
8
0
0
0
0
0
% H
% Ile:
0
0
8
0
0
0
16
0
0
0
8
8
8
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
8
0
0
0
0
8
0
% K
% Leu:
16
8
0
0
8
0
0
16
8
0
16
0
0
24
39
% L
% Met:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
16
0
0
8
0
0
0
0
0
0
8
0
% N
% Pro:
39
31
8
24
16
8
0
0
8
16
0
8
16
0
0
% P
% Gln:
8
0
0
0
0
0
0
0
8
8
0
16
0
16
0
% Q
% Arg:
0
8
0
0
16
8
0
16
39
0
47
0
8
8
0
% R
% Ser:
8
24
16
31
0
24
16
31
16
24
8
24
16
0
16
% S
% Thr:
8
0
8
0
0
0
0
0
0
8
8
16
16
0
8
% T
% Val:
16
8
8
0
16
0
24
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _