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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PNPT1
All Species:
36.06
Human Site:
S474
Identified Species:
72.12
UniProt:
Q8TCS8
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8TCS8
NP_149100.2
783
85951
S474
P
F
T
I
R
V
T
S
E
V
L
E
S
N
G
Chimpanzee
Pan troglodytes
XP_515490
783
85807
S474
P
F
T
I
R
V
T
S
E
V
L
E
S
N
G
Rhesus Macaque
Macaca mulatta
XP_001112421
754
83172
C454
S
S
S
M
A
S
A
C
G
G
S
L
A
L
M
Dog
Lupus familis
XP_538497
789
86661
S479
P
F
T
I
R
V
T
S
E
V
L
E
S
N
G
Cat
Felis silvestris
Mouse
Mus musculus
Q8K1R3
783
85664
S474
P
F
T
I
R
V
T
S
E
V
L
E
S
N
G
Rat
Rattus norvegicus
NP_001135843
784
85879
S474
P
F
T
I
R
V
T
S
E
V
L
E
S
N
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510386
764
83291
S454
P
F
T
M
R
V
T
S
E
V
L
E
S
N
G
Chicken
Gallus gallus
XP_419282
728
80301
A431
S
N
G
S
S
S
M
A
S
A
C
G
G
S
L
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_651867
771
84935
S472
P
F
T
V
R
L
T
S
E
V
L
E
S
N
G
Honey Bee
Apis mellifera
XP_396984
770
86395
S470
P
F
A
I
R
L
T
S
E
V
L
E
S
N
G
Nematode Worm
Caenorhab. elegans
NP_497324
738
81839
D441
L
K
N
L
F
P
A
D
F
P
Y
A
T
R
L
Sea Urchin
Strong. purpuratus
XP_788673
981
108251
S652
P
F
T
I
R
L
T
S
E
V
L
E
S
N
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
90
91
N.A.
90.9
91.5
N.A.
82.5
75.2
N.A.
N.A.
N.A.
54.4
51.7
39.8
49
Protein Similarity:
100
99.8
92.3
95.4
N.A.
96.3
96
N.A.
91.3
86.3
N.A.
N.A.
N.A.
71.7
69.5
56.1
62.7
P-Site Identity:
100
100
0
100
N.A.
100
100
N.A.
93.3
0
N.A.
N.A.
N.A.
86.6
86.6
0
93.3
P-Site Similarity:
100
100
20
100
N.A.
100
100
N.A.
100
13.3
N.A.
N.A.
N.A.
100
93.3
13.3
100
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
9
0
9
0
17
9
0
9
0
9
9
0
0
% A
% Cys:
0
0
0
0
0
0
0
9
0
0
9
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
9
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
75
0
0
75
0
0
0
% E
% Phe:
0
75
0
0
9
0
0
0
9
0
0
0
0
0
0
% F
% Gly:
0
0
9
0
0
0
0
0
9
9
0
9
9
0
75
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
59
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
9
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
9
0
0
9
0
25
0
0
0
0
75
9
0
9
17
% L
% Met:
0
0
0
17
0
0
9
0
0
0
0
0
0
0
9
% M
% Asn:
0
9
9
0
0
0
0
0
0
0
0
0
0
75
0
% N
% Pro:
75
0
0
0
0
9
0
0
0
9
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
75
0
0
0
0
0
0
0
0
9
0
% R
% Ser:
17
9
9
9
9
17
0
75
9
0
9
0
75
9
0
% S
% Thr:
0
0
67
0
0
0
75
0
0
0
0
0
9
0
0
% T
% Val:
0
0
0
9
0
50
0
0
0
75
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
9
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _