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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PNPT1 All Species: 22.73
Human Site: S91 Identified Species: 45.45
UniProt: Q8TCS8 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8TCS8 NP_149100.2 783 85951 S91 A V S K T K P S P S Q F M P L
Chimpanzee Pan troglodytes XP_515490 783 85807 S91 A V S K T K P S P S Q F M P L
Rhesus Macaque Macaca mulatta XP_001112421 754 83172 E92 E I G T S D K E I L T S R I I
Dog Lupus familis XP_538497 789 86661 S96 A V S K T K P S P S Q F M P L
Cat Felis silvestris
Mouse Mus musculus Q8K1R3 783 85664 S91 A V S K T K A S P S Q F M P L
Rat Rattus norvegicus NP_001135843 784 85879 S91 A V S K T K P S P S Q F M P L
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001510386 764 83291 R91 Q K A A A A G R I P T N Y L R
Chicken Gallus gallus XP_419282 728 80301 T69 L R R E L G T T D K E I L T S
Frog Xenopus laevis
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_651867 771 84935 L95 P G Q G F M P L V V D Y R L K
Honey Bee Apis mellifera XP_396984 770 86395 T96 N N S I I P L T V N Y R Q K A
Nematode Worm Caenorhab. elegans NP_497324 738 81839 V79 K Q G D G S G V P L Q V E Y R
Sea Urchin Strong. purpuratus XP_788673 981 108251 S271 A V S K K N S S S P G F L P L
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.7 90 91 N.A. 90.9 91.5 N.A. 82.5 75.2 N.A. N.A. N.A. 54.4 51.7 39.8 49
Protein Similarity: 100 99.8 92.3 95.4 N.A. 96.3 96 N.A. 91.3 86.3 N.A. N.A. N.A. 71.7 69.5 56.1 62.7
P-Site Identity: 100 100 0 100 N.A. 93.3 100 N.A. 0 0 N.A. N.A. N.A. 6.6 6.6 13.3 53.3
P-Site Similarity: 100 100 20 100 N.A. 93.3 100 N.A. 6.6 26.6 N.A. N.A. N.A. 13.3 20 13.3 60
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 50 0 9 9 9 9 9 0 0 0 0 0 0 0 9 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 9 0 9 0 0 9 0 9 0 0 0 0 % D
% Glu: 9 0 0 9 0 0 0 9 0 0 9 0 9 0 0 % E
% Phe: 0 0 0 0 9 0 0 0 0 0 0 50 0 0 0 % F
% Gly: 0 9 17 9 9 9 17 0 0 0 9 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 9 0 9 9 0 0 0 17 0 0 9 0 9 9 % I
% Lys: 9 9 0 50 9 42 9 0 0 9 0 0 0 9 9 % K
% Leu: 9 0 0 0 9 0 9 9 0 17 0 0 17 17 50 % L
% Met: 0 0 0 0 0 9 0 0 0 0 0 0 42 0 0 % M
% Asn: 9 9 0 0 0 9 0 0 0 9 0 9 0 0 0 % N
% Pro: 9 0 0 0 0 9 42 0 50 17 0 0 0 50 0 % P
% Gln: 9 9 9 0 0 0 0 0 0 0 50 0 9 0 0 % Q
% Arg: 0 9 9 0 0 0 0 9 0 0 0 9 17 0 17 % R
% Ser: 0 0 59 0 9 9 9 50 9 42 0 9 0 0 9 % S
% Thr: 0 0 0 9 42 0 9 17 0 0 17 0 0 9 0 % T
% Val: 0 50 0 0 0 0 0 9 17 9 0 9 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 9 9 9 9 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _