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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PNPT1
All Species:
24.24
Human Site:
Y527
Identified Species:
48.48
UniProt:
Q8TCS8
Number Species:
11
Phosphosite Substitution
Charge Score:
0.36
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8TCS8
NP_149100.2
783
85951
Y527
E
K
G
E
I
E
D
Y
R
L
L
T
D
I
L
Chimpanzee
Pan troglodytes
XP_515490
783
85807
Y527
E
K
G
E
I
E
D
Y
R
L
L
T
D
I
L
Rhesus Macaque
Macaca mulatta
XP_001112421
754
83172
D507
G
I
E
D
Y
N
G
D
M
D
F
K
I
A
G
Dog
Lupus familis
XP_538497
789
86661
Y532
D
K
G
E
I
E
D
Y
R
L
L
T
D
I
L
Cat
Felis silvestris
Mouse
Mus musculus
Q8K1R3
783
85664
Y527
E
K
G
E
I
E
D
Y
R
L
L
T
D
I
L
Rat
Rattus norvegicus
NP_001135843
784
85879
Y527
E
K
G
E
I
E
D
Y
R
L
L
T
D
I
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510386
764
83291
Y507
E
K
E
E
I
E
D
Y
R
L
M
T
D
I
L
Chicken
Gallus gallus
XP_419282
728
80301
Y484
D
I
L
G
I
E
D
Y
Y
G
D
M
D
F
K
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_651867
771
84935
D525
D
D
T
K
H
L
Q
D
Y
R
I
L
T
D
I
Honey Bee
Apis mellifera
XP_396984
770
86395
D523
T
A
D
L
K
E
T
D
Y
K
I
L
T
D
I
Nematode Worm
Caenorhab. elegans
NP_497324
738
81839
A494
I
G
L
I
S
D
E
A
E
P
E
T
K
Y
R
Sea Urchin
Strong. purpuratus
XP_788673
981
108251
D705
D
D
I
F
T
I
K
D
H
R
I
V
T
D
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
90
91
N.A.
90.9
91.5
N.A.
82.5
75.2
N.A.
N.A.
N.A.
54.4
51.7
39.8
49
Protein Similarity:
100
99.8
92.3
95.4
N.A.
96.3
96
N.A.
91.3
86.3
N.A.
N.A.
N.A.
71.7
69.5
56.1
62.7
P-Site Identity:
100
100
0
93.3
N.A.
100
100
N.A.
86.6
33.3
N.A.
N.A.
N.A.
0
6.6
6.6
6.6
P-Site Similarity:
100
100
6.6
100
N.A.
100
100
N.A.
93.3
40
N.A.
N.A.
N.A.
26.6
20
20
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
9
0
0
0
0
0
9
0
0
0
0
0
9
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
34
17
9
9
0
9
59
34
0
9
9
0
59
25
0
% D
% Glu:
42
0
17
50
0
67
9
0
9
0
9
0
0
0
0
% E
% Phe:
0
0
0
9
0
0
0
0
0
0
9
0
0
9
0
% F
% Gly:
9
9
42
9
0
0
9
0
0
9
0
0
0
0
9
% G
% His:
0
0
0
0
9
0
0
0
9
0
0
0
0
0
0
% H
% Ile:
9
17
9
9
59
9
0
0
0
0
25
0
9
50
17
% I
% Lys:
0
50
0
9
9
0
9
0
0
9
0
9
9
0
9
% K
% Leu:
0
0
17
9
0
9
0
0
0
50
42
17
0
0
59
% L
% Met:
0
0
0
0
0
0
0
0
9
0
9
9
0
0
0
% M
% Asn:
0
0
0
0
0
9
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
9
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
9
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
50
17
0
0
0
0
9
% R
% Ser:
0
0
0
0
9
0
0
0
0
0
0
0
0
0
0
% S
% Thr:
9
0
9
0
9
0
9
0
0
0
0
59
25
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
9
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
9
0
0
59
25
0
0
0
0
9
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _