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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PNPT1 All Species: 26.97
Human Site: Y626 Identified Species: 53.94
UniProt: Q8TCS8 Number Species: 11
    Phosphosite Substitution
    Charge Score: -0.18
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8TCS8 NP_149100.2 783 85951 Y626 K F V G P G G Y N L K K L Q A
Chimpanzee Pan troglodytes XP_515490 783 85807 Y626 K F V G P G G Y N L K K L Q A
Rhesus Macaque Macaca mulatta XP_001112421 754 83172 A598 Y N L K K L Q A E T G V T I S
Dog Lupus familis XP_538497 789 86661 Y631 K F V G P G G Y H L K K L Q A
Cat Felis silvestris
Mouse Mus musculus Q8K1R3 783 85664 Y626 K F V G P G G Y H L K K L Q A
Rat Rattus norvegicus NP_001135843 784 85879 Y626 K F I G P G G Y H L K K L Q A
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001510386 764 83291 Y606 K F V G P G G Y N I K K L Q A
Chicken Gallus gallus XP_419282 728 80301 K574 G P G A Y N L K K L Q A K T G
Frog Xenopus laevis
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_651867 771 84935 Q615 T L T V E P Q Q R A Q L I G P
Honey Bee Apis mellifera XP_396984 770 86395 H616 V P I H Q R R H F L G I G G L
Nematode Worm Caenorhab. elegans NP_497324 738 81839 R584 V P I I Q S M R I E P H K R V
Sea Urchin Strong. purpuratus XP_788673 981 108251 Y804 K F I G P G G Y N L K K L R V
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.7 90 91 N.A. 90.9 91.5 N.A. 82.5 75.2 N.A. N.A. N.A. 54.4 51.7 39.8 49
Protein Similarity: 100 99.8 92.3 95.4 N.A. 96.3 96 N.A. 91.3 86.3 N.A. N.A. N.A. 71.7 69.5 56.1 62.7
P-Site Identity: 100 100 0 93.3 N.A. 93.3 86.6 N.A. 93.3 6.6 N.A. N.A. N.A. 0 6.6 0 80
P-Site Similarity: 100 100 13.3 100 N.A. 100 100 N.A. 100 13.3 N.A. N.A. N.A. 13.3 20 13.3 93.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 9 0 0 0 9 0 9 0 9 0 0 50 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 9 0 0 0 9 9 0 0 0 0 0 % E
% Phe: 0 59 0 0 0 0 0 0 9 0 0 0 0 0 0 % F
% Gly: 9 0 9 59 0 59 59 0 0 0 17 0 9 17 9 % G
% His: 0 0 0 9 0 0 0 9 25 0 0 9 0 0 0 % H
% Ile: 0 0 34 9 0 0 0 0 9 9 0 9 9 9 0 % I
% Lys: 59 0 0 9 9 0 0 9 9 0 59 59 17 0 0 % K
% Leu: 0 9 9 0 0 9 9 0 0 67 0 9 59 0 9 % L
% Met: 0 0 0 0 0 0 9 0 0 0 0 0 0 0 0 % M
% Asn: 0 9 0 0 0 9 0 0 34 0 0 0 0 0 0 % N
% Pro: 0 25 0 0 59 9 0 0 0 0 9 0 0 0 9 % P
% Gln: 0 0 0 0 17 0 17 9 0 0 17 0 0 50 0 % Q
% Arg: 0 0 0 0 0 9 9 9 9 0 0 0 0 17 0 % R
% Ser: 0 0 0 0 0 9 0 0 0 0 0 0 0 0 9 % S
% Thr: 9 0 9 0 0 0 0 0 0 9 0 0 9 9 0 % T
% Val: 17 0 42 9 0 0 0 0 0 0 0 9 0 0 17 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 9 0 0 0 9 0 0 59 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _