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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CERK
All Species:
17.27
Human Site:
S128
Identified Species:
38
UniProt:
Q8TCT0
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8TCT0
NP_073603.2
537
59977
S128
E
M
L
E
K
L
T
S
R
P
K
H
L
L
V
Chimpanzee
Pan troglodytes
XP_001137835
537
59959
S128
E
M
L
E
K
L
T
S
R
P
K
H
L
L
V
Rhesus Macaque
Macaca mulatta
XP_001111087
537
59920
S128
E
M
L
E
K
L
T
S
R
P
K
H
L
L
V
Dog
Lupus familis
XP_531694
525
59050
I125
P
K
H
L
L
V
F
I
N
P
F
G
G
K
G
Cat
Felis silvestris
Mouse
Mus musculus
Q8K4Q7
531
59793
S128
G
L
L
E
S
L
T
S
R
P
K
H
L
L
V
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506327
542
60889
T128
E
S
L
E
K
L
T
T
R
P
K
H
L
L
V
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001074148
574
64000
R129
H
S
P
S
R
P
H
R
L
L
V
F
I
N
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_730923
687
75672
P198
I
R
L
H
S
S
S
P
T
R
M
R
V
R
R
Honey Bee
Apis mellifera
XP_391867
431
48985
I52
L
T
H
R
P
R
K
I
L
L
F
V
N
P
F
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_797972
615
68589
G152
T
A
L
Q
Q
G
H
G
R
P
K
R
L
H
V
Poplar Tree
Populus trichocarpa
XP_002328830
627
69383
G168
A
S
L
N
L
E
M
G
R
P
K
N
L
L
V
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
98.3
82.5
N.A.
83.9
N.A.
N.A.
69.3
N.A.
N.A.
42.3
N.A.
30.5
35
N.A.
36.7
Protein Similarity:
100
99.6
98.6
87.9
N.A.
90.3
N.A.
N.A.
80.2
N.A.
N.A.
59.4
N.A.
47
51.2
N.A.
57.2
P-Site Identity:
100
100
100
6.6
N.A.
80
N.A.
N.A.
86.6
N.A.
N.A.
0
N.A.
6.6
0
N.A.
40
P-Site Similarity:
100
100
100
13.3
N.A.
86.6
N.A.
N.A.
93.3
N.A.
N.A.
13.3
N.A.
20
0
N.A.
53.3
Percent
Protein Identity:
20.7
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
37.4
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
46.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
53.3
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
37
0
0
46
0
10
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
10
0
0
0
19
10
0
0
10
% F
% Gly:
10
0
0
0
0
10
0
19
0
0
0
10
10
0
10
% G
% His:
10
0
19
10
0
0
19
0
0
0
0
46
0
10
0
% H
% Ile:
10
0
0
0
0
0
0
19
0
0
0
0
10
0
0
% I
% Lys:
0
10
0
0
37
0
10
0
0
0
64
0
0
10
0
% K
% Leu:
10
10
73
10
19
46
0
0
19
19
0
0
64
55
0
% L
% Met:
0
28
0
0
0
0
10
0
0
0
10
0
0
0
0
% M
% Asn:
0
0
0
10
0
0
0
0
10
0
0
10
10
10
0
% N
% Pro:
10
0
10
0
10
10
0
10
0
73
0
0
0
10
10
% P
% Gln:
0
0
0
10
10
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
10
0
10
10
10
0
10
64
10
0
19
0
10
10
% R
% Ser:
0
28
0
10
19
10
10
37
0
0
0
0
0
0
0
% S
% Thr:
10
10
0
0
0
0
46
10
10
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
10
0
0
0
0
10
10
10
0
64
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _