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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CERK
All Species:
30.3
Human Site:
S427
Identified Species:
66.67
UniProt:
Q8TCT0
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8TCT0
NP_073603.2
537
59977
S427
L
I
L
I
R
K
C
S
R
F
N
F
L
R
F
Chimpanzee
Pan troglodytes
XP_001137835
537
59959
S427
L
I
L
I
R
K
C
S
R
F
N
F
L
R
F
Rhesus Macaque
Macaca mulatta
XP_001111087
537
59920
S427
L
I
L
I
R
K
C
S
R
F
N
F
L
R
F
Dog
Lupus familis
XP_531694
525
59050
S415
L
I
L
I
R
K
C
S
R
F
N
F
L
R
F
Cat
Felis silvestris
Mouse
Mus musculus
Q8K4Q7
531
59793
S427
L
I
L
I
R
K
C
S
R
F
N
F
L
R
F
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506327
542
60889
S427
L
I
L
V
R
K
C
S
R
F
N
F
L
R
Y
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001074148
574
64000
N430
L
I
L
V
R
D
T
N
P
L
S
F
L
T
Y
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_730923
687
75672
S559
L
I
L
V
K
K
T
S
L
L
N
N
V
R
F
Honey Bee
Apis mellifera
XP_391867
431
48985
L333
I
L
V
R
H
T
S
L
F
N
N
I
R
M
L
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_797972
615
68589
S451
L
V
L
V
R
Q
C
S
R
F
D
Y
L
R
H
Poplar Tree
Populus trichocarpa
XP_002328830
627
69383
R529
I
I
S
N
R
N
E
R
A
P
D
G
L
V
A
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
98.3
82.5
N.A.
83.9
N.A.
N.A.
69.3
N.A.
N.A.
42.3
N.A.
30.5
35
N.A.
36.7
Protein Similarity:
100
99.6
98.6
87.9
N.A.
90.3
N.A.
N.A.
80.2
N.A.
N.A.
59.4
N.A.
47
51.2
N.A.
57.2
P-Site Identity:
100
100
100
100
N.A.
100
N.A.
N.A.
86.6
N.A.
N.A.
40
N.A.
53.3
6.6
N.A.
60
P-Site Similarity:
100
100
100
100
N.A.
100
N.A.
N.A.
100
N.A.
N.A.
66.6
N.A.
73.3
26.6
N.A.
93.3
Percent
Protein Identity:
20.7
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
37.4
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
20
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
33.3
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
10
% A
% Cys:
0
0
0
0
0
0
64
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
10
0
0
0
0
19
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
10
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
10
64
0
64
0
0
55
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% G
% His:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
10
% H
% Ile:
19
82
0
46
0
0
0
0
0
0
0
10
0
0
0
% I
% Lys:
0
0
0
0
10
64
0
0
0
0
0
0
0
0
0
% K
% Leu:
82
10
82
0
0
0
0
10
10
19
0
0
82
0
10
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% M
% Asn:
0
0
0
10
0
10
0
10
0
10
73
10
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
10
10
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
10
82
0
0
10
64
0
0
0
10
73
0
% R
% Ser:
0
0
10
0
0
0
10
73
0
0
10
0
0
0
0
% S
% Thr:
0
0
0
0
0
10
19
0
0
0
0
0
0
10
0
% T
% Val:
0
10
10
37
0
0
0
0
0
0
0
0
10
10
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
19
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _