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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CERK
All Species:
13.03
Human Site:
Y181
Identified Species:
28.67
UniProt:
Q8TCT0
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8TCT0
NP_073603.2
537
59977
Y181
N
Q
A
K
E
T
L
Y
E
I
N
I
D
K
Y
Chimpanzee
Pan troglodytes
XP_001137835
537
59959
Y181
N
Q
A
K
E
T
L
Y
E
I
N
I
D
K
Y
Rhesus Macaque
Macaca mulatta
XP_001111087
537
59920
Y181
N
Q
A
K
E
T
L
Y
E
I
N
I
D
K
Y
Dog
Lupus familis
XP_531694
525
59050
I171
A
K
E
S
L
Y
E
I
N
I
D
K
Y
D
G
Cat
Felis silvestris
Mouse
Mus musculus
Q8K4Q7
531
59793
Y181
N
Q
A
K
E
T
L
Y
E
I
N
T
D
S
Y
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506327
542
60889
L181
N
H
A
K
D
S
L
L
E
I
N
I
E
K
Y
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001074148
574
64000
L178
N
Q
A
R
D
Y
I
L
K
K
D
L
T
G
F
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_730923
687
75672
L253
A
N
Q
V
K
D
I
L
L
S
H
D
L
G
V
Honey Bee
Apis mellifera
XP_391867
431
48985
I98
R
V
N
H
I
R
D
I
L
L
S
T
D
L
T
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_797972
615
68589
Q205
D
H
A
K
S
L
M
Q
M
M
D
L
T
G
I
Poplar Tree
Populus trichocarpa
XP_002328830
627
69383
N291
V
T
E
A
T
C
Q
N
E
D
H
S
P
L
L
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
98.3
82.5
N.A.
83.9
N.A.
N.A.
69.3
N.A.
N.A.
42.3
N.A.
30.5
35
N.A.
36.7
Protein Similarity:
100
99.6
98.6
87.9
N.A.
90.3
N.A.
N.A.
80.2
N.A.
N.A.
59.4
N.A.
47
51.2
N.A.
57.2
P-Site Identity:
100
100
100
6.6
N.A.
86.6
N.A.
N.A.
66.6
N.A.
N.A.
20
N.A.
0
6.6
N.A.
13.3
P-Site Similarity:
100
100
100
20
N.A.
86.6
N.A.
N.A.
86.6
N.A.
N.A.
66.6
N.A.
20
20
N.A.
46.6
Percent
Protein Identity:
20.7
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
37.4
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
19
0
64
10
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% C
% Asp:
10
0
0
0
19
10
10
0
0
10
28
10
46
10
0
% D
% Glu:
0
0
19
0
37
0
10
0
55
0
0
0
10
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
28
10
% G
% His:
0
19
0
10
0
0
0
0
0
0
19
0
0
0
0
% H
% Ile:
0
0
0
0
10
0
19
19
0
55
0
37
0
0
10
% I
% Lys:
0
10
0
55
10
0
0
0
10
10
0
10
0
37
0
% K
% Leu:
0
0
0
0
10
10
46
28
19
10
0
19
10
19
10
% L
% Met:
0
0
0
0
0
0
10
0
10
10
0
0
0
0
0
% M
% Asn:
55
10
10
0
0
0
0
10
10
0
46
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% P
% Gln:
0
46
10
0
0
0
10
10
0
0
0
0
0
0
0
% Q
% Arg:
10
0
0
10
0
10
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
10
10
10
0
0
0
10
10
10
0
10
0
% S
% Thr:
0
10
0
0
10
37
0
0
0
0
0
19
19
0
10
% T
% Val:
10
10
0
10
0
0
0
0
0
0
0
0
0
0
10
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
19
0
37
0
0
0
0
10
0
46
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _