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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SPPL3
All Species:
18.79
Human Site:
S233
Identified Species:
37.58
UniProt:
Q8TCT6
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8TCT6
NP_620584.2
385
42563
S233
D
N
P
L
D
V
L
S
R
K
L
H
L
G
P
Chimpanzee
Pan troglodytes
XP_001163083
347
38069
N203
R
K
L
H
L
G
P
N
V
G
R
D
V
P
R
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_543427
384
42259
S232
D
N
P
L
D
V
L
S
R
K
L
H
L
G
P
Cat
Felis silvestris
Mouse
Mus musculus
Q9CUS9
384
42230
S232
D
N
P
L
D
V
L
S
K
K
L
H
L
G
P
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506245
447
48731
S295
D
N
P
L
D
V
L
S
R
K
L
H
L
G
P
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001079617
379
41677
S231
D
N
P
L
D
V
L
S
R
K
L
H
L
G
P
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_651437
417
45424
A268
D
N
P
V
G
I
V
A
R
K
L
H
L
G
G
Honey Bee
Apis mellifera
XP_393189
393
43467
A243
D
N
P
V
N
L
V
A
R
R
L
H
L
G
G
Nematode Worm
Caenorhab. elegans
P49049
468
52775
Y248
F
K
I
D
F
D
R
Y
D
I
I
A
L
L
M
Sea Urchin
Strong. purpuratus
XP_796162
390
43502
A241
D
N
P
V
G
M
M
A
K
K
F
N
L
G
V
Poplar Tree
Populus trichocarpa
XP_002318813
371
40878
L223
T
V
A
N
S
L
S
L
P
G
L
Q
L
I
T
Maize
Zea mays
NP_001151225
372
41067
L223
T
V
A
N
K
L
S
L
P
G
L
Q
L
I
T
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
86.7
N.A.
95.3
N.A.
95.8
N.A.
N.A.
78.3
N.A.
91.1
N.A.
N.A.
61.3
66.1
23.9
70.5
Protein Similarity:
100
87.5
N.A.
96.8
N.A.
96.8
N.A.
N.A.
81.4
N.A.
94.2
N.A.
N.A.
75.3
79.9
40.3
83.8
P-Site Identity:
100
0
N.A.
100
N.A.
93.3
N.A.
N.A.
100
N.A.
100
N.A.
N.A.
60
53.3
6.6
40
P-Site Similarity:
100
13.3
N.A.
100
N.A.
100
N.A.
N.A.
100
N.A.
100
N.A.
N.A.
86.6
93.3
13.3
80
Percent
Protein Identity:
34.8
34.5
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
54.8
54.5
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
13.3
13.3
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
20
20
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
17
0
0
0
0
25
0
0
0
9
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
67
0
0
9
42
9
0
0
9
0
0
9
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
9
0
0
0
9
0
0
0
0
0
9
0
0
0
0
% F
% Gly:
0
0
0
0
17
9
0
0
0
25
0
0
0
67
17
% G
% His:
0
0
0
9
0
0
0
0
0
0
0
59
0
0
0
% H
% Ile:
0
0
9
0
0
9
0
0
0
9
9
0
0
17
0
% I
% Lys:
0
17
0
0
9
0
0
0
17
59
0
0
0
0
0
% K
% Leu:
0
0
9
42
9
25
42
17
0
0
75
0
92
9
0
% L
% Met:
0
0
0
0
0
9
9
0
0
0
0
0
0
0
9
% M
% Asn:
0
67
0
17
9
0
0
9
0
0
0
9
0
0
0
% N
% Pro:
0
0
67
0
0
0
9
0
17
0
0
0
0
9
42
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
17
0
0
0
% Q
% Arg:
9
0
0
0
0
0
9
0
50
9
9
0
0
0
9
% R
% Ser:
0
0
0
0
9
0
17
42
0
0
0
0
0
0
0
% S
% Thr:
17
0
0
0
0
0
0
0
0
0
0
0
0
0
17
% T
% Val:
0
17
0
25
0
42
17
0
9
0
0
0
9
0
9
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
9
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _