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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SPPL3
All Species:
20.61
Human Site:
S260
Identified Species:
41.21
UniProt:
Q8TCT6
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8TCT6
NP_620584.2
385
42563
S260
G
K
L
V
F
P
S
S
T
G
S
H
F
S
M
Chimpanzee
Pan troglodytes
XP_001163083
347
38069
S228
S
S
T
G
S
H
F
S
M
L
G
I
G
D
I
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_543427
384
42259
S259
G
K
L
V
F
P
S
S
T
G
S
H
F
S
M
Cat
Felis silvestris
Mouse
Mus musculus
Q9CUS9
384
42230
S259
G
K
L
V
F
P
S
S
T
G
S
H
F
S
M
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506245
447
48731
S322
G
K
L
V
F
P
S
S
T
G
S
H
F
S
M
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001079617
379
41677
S258
G
K
L
V
F
P
S
S
T
G
S
H
F
S
M
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_651437
417
45424
L294
G
K
L
V
F
P
S
L
H
N
T
G
H
F
S
Honey Bee
Apis mellifera
XP_393189
393
43467
M269
G
K
L
V
F
P
S
M
H
Q
A
G
H
F
S
Nematode Worm
Caenorhab. elegans
P49049
468
52775
I274
R
H
W
I
T
N
N
I
I
G
V
S
F
S
I
Sea Urchin
Strong. purpuratus
XP_796162
390
43502
M266
G
K
L
I
F
P
S
M
H
N
A
G
H
F
S
Poplar Tree
Populus trichocarpa
XP_002318813
371
40878
T249
P
R
N
L
F
S
S
T
A
P
G
G
N
T
T
Maize
Zea mays
NP_001151225
372
41067
V250
R
N
L
L
G
G
I
V
P
G
S
N
P
G
D
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
86.7
N.A.
95.3
N.A.
95.8
N.A.
N.A.
78.3
N.A.
91.1
N.A.
N.A.
61.3
66.1
23.9
70.5
Protein Similarity:
100
87.5
N.A.
96.8
N.A.
96.8
N.A.
N.A.
81.4
N.A.
94.2
N.A.
N.A.
75.3
79.9
40.3
83.8
P-Site Identity:
100
6.6
N.A.
100
N.A.
100
N.A.
N.A.
100
N.A.
100
N.A.
N.A.
46.6
46.6
20
40
P-Site Similarity:
100
13.3
N.A.
100
N.A.
100
N.A.
N.A.
100
N.A.
100
N.A.
N.A.
53.3
53.3
40
53.3
Percent
Protein Identity:
34.8
34.5
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
54.8
54.5
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
13.3
20
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
40
33.3
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
9
0
17
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
9
9
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
75
0
9
0
0
0
0
0
50
25
0
% F
% Gly:
67
0
0
9
9
9
0
0
0
59
17
34
9
9
0
% G
% His:
0
9
0
0
0
9
0
0
25
0
0
42
25
0
0
% H
% Ile:
0
0
0
17
0
0
9
9
9
0
0
9
0
0
17
% I
% Lys:
0
67
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
75
17
0
0
0
9
0
9
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
17
9
0
0
0
0
0
42
% M
% Asn:
0
9
9
0
0
9
9
0
0
17
0
9
9
0
0
% N
% Pro:
9
0
0
0
0
67
0
0
9
9
0
0
9
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
9
0
0
0
0
0
% Q
% Arg:
17
9
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
9
9
0
0
9
9
75
50
0
0
50
9
0
50
25
% S
% Thr:
0
0
9
0
9
0
0
9
42
0
9
0
0
9
9
% T
% Val:
0
0
0
59
0
0
0
9
0
0
9
0
0
0
0
% V
% Trp:
0
0
9
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _