KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SPPL3
All Species:
13.64
Human Site:
S297
Identified Species:
27.27
UniProt:
Q8TCT6
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8TCT6
NP_620584.2
385
42563
S297
K
K
Q
A
S
G
D
S
C
G
A
P
G
P
A
Chimpanzee
Pan troglodytes
XP_001163083
347
38069
C260
K
Q
A
S
G
D
S
C
G
A
P
G
P
A
N
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_543427
384
42259
S296
K
K
Q
A
N
G
D
S
C
G
A
S
G
P
A
Cat
Felis silvestris
Mouse
Mus musculus
Q9CUS9
384
42230
S296
K
K
Q
A
S
G
D
S
C
G
A
P
G
P
A
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506245
447
48731
S359
K
K
Q
A
N
S
D
S
C
G
A
Q
G
P
G
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001079617
379
41677
A291
Y
D
N
Y
K
K
Q
A
T
S
D
S
Q
G
A
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_651437
417
45424
V330
A
Y
K
K
A
Q
G
V
T
S
D
P
T
L
S
Honey Bee
Apis mellifera
XP_393189
393
43467
P306
Y
K
K
T
Q
L
L
P
G
G
C
E
T
G
V
Nematode Worm
Caenorhab. elegans
P49049
468
52775
V372
R
R
F
D
Y
R
V
V
Q
T
T
A
E
S
K
Sea Urchin
Strong. purpuratus
XP_796162
390
43502
T303
Y
K
R
Q
Q
T
D
T
L
A
P
A
P
I
L
Poplar Tree
Populus trichocarpa
XP_002318813
371
40878
K283
V
L
C
F
D
Y
R
K
S
R
D
P
V
N
L
Maize
Zea mays
NP_001151225
372
41067
L284
L
F
F
D
N
R
K
L
K
D
V
N
V
V
P
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
86.7
N.A.
95.3
N.A.
95.8
N.A.
N.A.
78.3
N.A.
91.1
N.A.
N.A.
61.3
66.1
23.9
70.5
Protein Similarity:
100
87.5
N.A.
96.8
N.A.
96.8
N.A.
N.A.
81.4
N.A.
94.2
N.A.
N.A.
75.3
79.9
40.3
83.8
P-Site Identity:
100
6.6
N.A.
86.6
N.A.
100
N.A.
N.A.
73.3
N.A.
6.6
N.A.
N.A.
6.6
13.3
0
13.3
P-Site Similarity:
100
20
N.A.
93.3
N.A.
100
N.A.
N.A.
80
N.A.
13.3
N.A.
N.A.
26.6
20
13.3
26.6
Percent
Protein Identity:
34.8
34.5
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
54.8
54.5
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
6.6
0
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
6.6
6.6
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
0
9
34
9
0
0
9
0
17
34
17
0
9
34
% A
% Cys:
0
0
9
0
0
0
0
9
34
0
9
0
0
0
0
% C
% Asp:
0
9
0
17
9
9
42
0
0
9
25
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
9
9
0
0
% E
% Phe:
0
9
17
9
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
9
25
9
0
17
42
0
9
34
17
9
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
9
0
% I
% Lys:
42
50
17
9
9
9
9
9
9
0
0
0
0
0
9
% K
% Leu:
9
9
0
0
0
9
9
9
9
0
0
0
0
9
17
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
9
0
25
0
0
0
0
0
0
9
0
9
9
% N
% Pro:
0
0
0
0
0
0
0
9
0
0
17
34
17
34
9
% P
% Gln:
0
9
34
9
17
9
9
0
9
0
0
9
9
0
0
% Q
% Arg:
9
9
9
0
0
17
9
0
0
9
0
0
0
0
0
% R
% Ser:
0
0
0
9
17
9
9
34
9
17
0
17
0
9
9
% S
% Thr:
0
0
0
9
0
9
0
9
17
9
9
0
17
0
0
% T
% Val:
9
0
0
0
0
0
9
17
0
0
9
0
17
9
9
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
25
9
0
9
9
9
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _