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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SPPL3 All Species: 15.76
Human Site: S307 Identified Species: 31.52
UniProt: Q8TCT6 Number Species: 11
    Phosphosite Substitution
    Charge Score: -0.09
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8TCT6 NP_620584.2 385 42563 S307 A P G P A N I S G R M Q K V S
Chimpanzee Pan troglodytes XP_001163083 347 38069 G270 P G P A N I S G R M Q K V S Y
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_543427 384 42259 S306 A S G P A N I S G R M Q K V S
Cat Felis silvestris
Mouse Mus musculus Q9CUS9 384 42230 S306 A P G P A N I S G R M Q K V S
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506245 447 48731 S369 A Q G P G N I S G R M Q K V S
Chicken Gallus gallus
Frog Xenopus laevis NP_001079617 379 41677 S301 D S Q G A P I S G R M Q K V S
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_651437 417 45424 R340 D P T L S P P R G V G S R L T
Honey Bee Apis mellifera XP_393189 393 43467 P316 C E T G V P P P R H I N R I S
Nematode Worm Caenorhab. elegans P49049 468 52775 Q382 T A E S K A P Q G S L K G R Y
Sea Urchin Strong. purpuratus XP_796162 390 43502 N313 P A P I L P P N S L S Q K V T
Poplar Tree Populus trichocarpa XP_002318813 371 40878 L293 D P V N L L D L Y S S K G Q K
Maize Zea mays NP_001151225 372 41067 V294 V N V V P S D V S P L R R R N
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 86.7 N.A. 95.3 N.A. 95.8 N.A. N.A. 78.3 N.A. 91.1 N.A. N.A. 61.3 66.1 23.9 70.5
Protein Similarity: 100 87.5 N.A. 96.8 N.A. 96.8 N.A. N.A. 81.4 N.A. 94.2 N.A. N.A. 75.3 79.9 40.3 83.8
P-Site Identity: 100 0 N.A. 93.3 N.A. 100 N.A. N.A. 86.6 N.A. 66.6 N.A. N.A. 13.3 6.6 6.6 20
P-Site Similarity: 100 6.6 N.A. 93.3 N.A. 100 N.A. N.A. 86.6 N.A. 66.6 N.A. N.A. 40 26.6 20 33.3
Percent
Protein Identity: 34.8 34.5 N.A. N.A. N.A. N.A.
Protein Similarity: 54.8 54.5 N.A. N.A. N.A. N.A.
P-Site Identity: 6.6 0 N.A. N.A. N.A. N.A.
P-Site Similarity: 13.3 33.3 N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 34 17 0 9 34 9 0 0 0 0 0 0 0 0 0 % A
% Cys: 9 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 25 0 0 0 0 0 17 0 0 0 0 0 0 0 0 % D
% Glu: 0 9 9 0 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 9 34 17 9 0 0 9 59 0 9 0 17 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 9 0 0 0 0 0 % H
% Ile: 0 0 0 9 0 9 42 0 0 0 9 0 0 9 0 % I
% Lys: 0 0 0 0 9 0 0 0 0 0 0 25 50 0 9 % K
% Leu: 0 0 0 9 17 9 0 9 0 9 17 0 0 9 0 % L
% Met: 0 0 0 0 0 0 0 0 0 9 42 0 0 0 0 % M
% Asn: 0 9 0 9 9 34 0 9 0 0 0 9 0 0 9 % N
% Pro: 17 34 17 34 9 34 34 9 0 9 0 0 0 0 0 % P
% Gln: 0 9 9 0 0 0 0 9 0 0 9 50 0 9 0 % Q
% Arg: 0 0 0 0 0 0 0 9 17 42 0 9 25 17 0 % R
% Ser: 0 17 0 9 9 9 9 42 17 17 17 9 0 9 50 % S
% Thr: 9 0 17 0 0 0 0 0 0 0 0 0 0 0 17 % T
% Val: 9 0 17 9 9 0 0 9 0 9 0 0 9 50 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 9 0 0 0 0 0 17 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _