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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SPPL3
All Species:
16.36
Human Site:
S375
Identified Species:
32.73
UniProt:
Q8TCT6
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.27
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8TCT6
NP_620584.2
385
42563
S375
M
W
S
E
P
F
H
S
K
S
S
S
S
R
F
Chimpanzee
Pan troglodytes
XP_001163083
347
38069
K338
W
S
E
P
F
H
S
K
S
S
S
S
R
F
L
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_543427
384
42259
S374
M
W
S
E
P
F
H
S
K
S
S
S
S
R
F
Cat
Felis silvestris
Mouse
Mus musculus
Q9CUS9
384
42230
S374
M
W
S
E
P
F
H
S
K
S
S
S
S
R
F
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506245
447
48731
S437
M
W
S
E
P
F
H
S
K
S
S
S
S
R
F
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001079617
379
41677
A369
M
W
S
E
P
F
H
A
K
A
S
S
P
R
F
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_651437
417
45424
A408
M
W
S
E
P
F
I
A
Q
Q
P
S
K
Q
L
Honey Bee
Apis mellifera
XP_393189
393
43467
S384
M
W
S
E
P
F
I
S
Q
Q
P
S
K
H
M
Nematode Worm
Caenorhab. elegans
P49049
468
52775
R450
L
W
N
Y
D
E
S
R
H
V
D
N
E
E
N
Sea Urchin
Strong. purpuratus
XP_796162
390
43502
K381
M
W
H
E
P
F
I
K
S
T
Q
N
K
Y
M
Poplar Tree
Populus trichocarpa
XP_002318813
371
40878
N361
L
W
E
G
S
M
S
N
V
N
D
K
A
R
Q
Maize
Zea mays
NP_001151225
372
41067
I362
L
W
E
G
S
G
T
I
L
N
D
K
A
R
L
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
86.7
N.A.
95.3
N.A.
95.8
N.A.
N.A.
78.3
N.A.
91.1
N.A.
N.A.
61.3
66.1
23.9
70.5
Protein Similarity:
100
87.5
N.A.
96.8
N.A.
96.8
N.A.
N.A.
81.4
N.A.
94.2
N.A.
N.A.
75.3
79.9
40.3
83.8
P-Site Identity:
100
20
N.A.
100
N.A.
100
N.A.
N.A.
100
N.A.
80
N.A.
N.A.
46.6
53.3
6.6
33.3
P-Site Similarity:
100
20
N.A.
100
N.A.
100
N.A.
N.A.
100
N.A.
93.3
N.A.
N.A.
66.6
60
26.6
46.6
Percent
Protein Identity:
34.8
34.5
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
54.8
54.5
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
13.3
13.3
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
40
33.3
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
17
0
9
0
0
17
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
9
0
0
0
0
0
25
0
0
0
0
% D
% Glu:
0
0
25
67
0
9
0
0
0
0
0
0
9
9
0
% E
% Phe:
0
0
0
0
9
67
0
0
0
0
0
0
0
9
42
% F
% Gly:
0
0
0
17
0
9
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
9
0
0
9
42
0
9
0
0
0
0
9
0
% H
% Ile:
0
0
0
0
0
0
25
9
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
17
42
0
0
17
25
0
0
% K
% Leu:
25
0
0
0
0
0
0
0
9
0
0
0
0
0
25
% L
% Met:
67
0
0
0
0
9
0
0
0
0
0
0
0
0
17
% M
% Asn:
0
0
9
0
0
0
0
9
0
17
0
17
0
0
9
% N
% Pro:
0
0
0
9
67
0
0
0
0
0
17
0
9
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
17
17
9
0
0
9
9
% Q
% Arg:
0
0
0
0
0
0
0
9
0
0
0
0
9
59
0
% R
% Ser:
0
9
59
0
17
0
25
42
17
42
50
67
34
0
0
% S
% Thr:
0
0
0
0
0
0
9
0
0
9
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
9
9
0
0
0
0
0
% V
% Trp:
9
92
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
9
0
0
0
0
0
0
0
0
0
9
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _