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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SPPL3
All Species:
13.64
Human Site:
S51
Identified Species:
27.27
UniProt:
Q8TCT6
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8TCT6
NP_620584.2
385
42563
S51
D
K
E
K
D
S
N
S
S
S
G
S
F
N
G
Chimpanzee
Pan troglodytes
XP_001163083
347
38069
D32
N
N
S
I
Q
T
I
D
S
T
Q
A
L
F
L
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_543427
384
42259
S51
D
K
E
K
D
N
S
S
S
S
G
S
F
N
G
Cat
Felis silvestris
Mouse
Mus musculus
Q9CUS9
384
42230
S51
D
K
E
K
D
S
N
S
S
S
G
S
F
N
G
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506245
447
48731
S114
D
K
E
K
D
S
N
S
S
S
G
S
F
N
G
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001079617
379
41677
G51
D
K
E
K
D
G
S
G
S
P
G
A
F
S
G
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_651437
417
45424
N81
E
R
E
Q
K
K
R
N
E
S
M
T
N
L
L
Honey Bee
Apis mellifera
XP_393189
393
43467
R53
E
R
E
K
E
K
E
R
G
N
L
L
T
G
I
Nematode Worm
Caenorhab. elegans
P49049
468
52775
G61
D
K
K
R
L
I
E
G
S
I
T
M
R
E
A
Sea Urchin
Strong. purpuratus
XP_796162
390
43502
K54
E
R
L
Q
R
E
E
K
D
N
A
L
S
G
P
Poplar Tree
Populus trichocarpa
XP_002318813
371
40878
I51
L
D
L
S
E
A
S
I
T
L
D
R
S
Q
A
Maize
Zea mays
NP_001151225
372
41067
I51
L
D
F
S
E
A
S
I
T
L
D
R
S
Q
A
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
86.7
N.A.
95.3
N.A.
95.8
N.A.
N.A.
78.3
N.A.
91.1
N.A.
N.A.
61.3
66.1
23.9
70.5
Protein Similarity:
100
87.5
N.A.
96.8
N.A.
96.8
N.A.
N.A.
81.4
N.A.
94.2
N.A.
N.A.
75.3
79.9
40.3
83.8
P-Site Identity:
100
6.6
N.A.
86.6
N.A.
100
N.A.
N.A.
100
N.A.
60
N.A.
N.A.
13.3
13.3
20
0
P-Site Similarity:
100
33.3
N.A.
100
N.A.
100
N.A.
N.A.
100
N.A.
80
N.A.
N.A.
46.6
40
33.3
26.6
Percent
Protein Identity:
34.8
34.5
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
54.8
54.5
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
0
0
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
26.6
26.6
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
17
0
0
0
0
9
17
0
0
25
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
50
17
0
0
42
0
0
9
9
0
17
0
0
0
0
% D
% Glu:
25
0
59
0
25
9
25
0
9
0
0
0
0
9
0
% E
% Phe:
0
0
9
0
0
0
0
0
0
0
0
0
42
9
0
% F
% Gly:
0
0
0
0
0
9
0
17
9
0
42
0
0
17
42
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
9
0
9
9
17
0
9
0
0
0
0
9
% I
% Lys:
0
50
9
50
9
17
0
9
0
0
0
0
0
0
0
% K
% Leu:
17
0
17
0
9
0
0
0
0
17
9
17
9
9
17
% L
% Met:
0
0
0
0
0
0
0
0
0
0
9
9
0
0
0
% M
% Asn:
9
9
0
0
0
9
25
9
0
17
0
0
9
34
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
9
0
0
0
0
9
% P
% Gln:
0
0
0
17
9
0
0
0
0
0
9
0
0
17
0
% Q
% Arg:
0
25
0
9
9
0
9
9
0
0
0
17
9
0
0
% R
% Ser:
0
0
9
17
0
25
34
34
59
42
0
34
25
9
0
% S
% Thr:
0
0
0
0
0
9
0
0
17
9
9
9
9
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _