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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SPPL3
All Species:
11.52
Human Site:
S55
Identified Species:
23.03
UniProt:
Q8TCT6
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.18
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8TCT6
NP_620584.2
385
42563
S55
D
S
N
S
S
S
G
S
F
N
G
E
Q
E
P
Chimpanzee
Pan troglodytes
XP_001163083
347
38069
A36
Q
T
I
D
S
T
Q
A
L
F
L
P
I
G
A
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_543427
384
42259
S55
D
N
S
S
S
S
G
S
F
N
G
N
S
T
N
Cat
Felis silvestris
Mouse
Mus musculus
Q9CUS9
384
42230
S55
D
S
N
S
S
S
G
S
F
N
G
N
S
T
N
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506245
447
48731
S118
D
S
N
S
S
S
G
S
F
N
G
N
S
T
N
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001079617
379
41677
A55
D
G
S
G
S
P
G
A
F
S
G
N
G
S
N
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_651437
417
45424
T85
K
K
R
N
E
S
M
T
N
L
L
T
G
E
P
Honey Bee
Apis mellifera
XP_393189
393
43467
L57
E
K
E
R
G
N
L
L
T
G
I
L
S
N
S
Nematode Worm
Caenorhab. elegans
P49049
468
52775
M65
L
I
E
G
S
I
T
M
R
E
A
R
K
F
P
Sea Urchin
Strong. purpuratus
XP_796162
390
43502
L58
R
E
E
K
D
N
A
L
S
G
P
P
P
G
N
Poplar Tree
Populus trichocarpa
XP_002318813
371
40878
R55
E
A
S
I
T
L
D
R
S
Q
A
L
M
I
P
Maize
Zea mays
NP_001151225
372
41067
R55
E
A
S
I
T
L
D
R
S
Q
A
L
M
I
P
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
86.7
N.A.
95.3
N.A.
95.8
N.A.
N.A.
78.3
N.A.
91.1
N.A.
N.A.
61.3
66.1
23.9
70.5
Protein Similarity:
100
87.5
N.A.
96.8
N.A.
96.8
N.A.
N.A.
81.4
N.A.
94.2
N.A.
N.A.
75.3
79.9
40.3
83.8
P-Site Identity:
100
6.6
N.A.
60
N.A.
73.3
N.A.
N.A.
73.3
N.A.
33.3
N.A.
N.A.
20
0
13.3
0
P-Site Similarity:
100
26.6
N.A.
73.3
N.A.
73.3
N.A.
N.A.
73.3
N.A.
53.3
N.A.
N.A.
33.3
13.3
20
6.6
Percent
Protein Identity:
34.8
34.5
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
54.8
54.5
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
6.6
6.6
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
33.3
33.3
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
17
0
0
0
0
9
17
0
0
25
0
0
0
9
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
42
0
0
9
9
0
17
0
0
0
0
0
0
0
0
% D
% Glu:
25
9
25
0
9
0
0
0
0
9
0
9
0
17
0
% E
% Phe:
0
0
0
0
0
0
0
0
42
9
0
0
0
9
0
% F
% Gly:
0
9
0
17
9
0
42
0
0
17
42
0
17
17
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
9
9
17
0
9
0
0
0
0
9
0
9
17
0
% I
% Lys:
9
17
0
9
0
0
0
0
0
0
0
0
9
0
0
% K
% Leu:
9
0
0
0
0
17
9
17
9
9
17
25
0
0
0
% L
% Met:
0
0
0
0
0
0
9
9
0
0
0
0
17
0
0
% M
% Asn:
0
9
25
9
0
17
0
0
9
34
0
34
0
9
42
% N
% Pro:
0
0
0
0
0
9
0
0
0
0
9
17
9
0
42
% P
% Gln:
9
0
0
0
0
0
9
0
0
17
0
0
9
0
0
% Q
% Arg:
9
0
9
9
0
0
0
17
9
0
0
9
0
0
0
% R
% Ser:
0
25
34
34
59
42
0
34
25
9
0
0
34
9
9
% S
% Thr:
0
9
0
0
17
9
9
9
9
0
0
9
0
25
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _