KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SPPL2B
All Species:
16.67
Human Site:
S441
Identified Species:
45.83
UniProt:
Q8TCT7
Number Species:
8
Phosphosite Substitution
Charge Score:
0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8TCT7
NP_001070706.1
592
64644
S441
R
F
D
I
Q
V
Q
S
S
R
V
Y
F
V
A
Chimpanzee
Pan troglodytes
XP_523673
684
74537
S468
R
F
D
V
Q
V
C
S
R
Q
V
Y
F
V
A
Rhesus Macaque
Macaca mulatta
XP_001097918
495
54847
A347
I
R
L
P
T
F
K
A
C
T
L
L
L
L
V
Dog
Lupus familis
XP_542189
880
94252
S569
R
F
D
I
Q
V
Q
S
S
R
V
Y
F
V
A
Cat
Felis silvestris
Mouse
Mus musculus
Q3TD49
578
63805
V422
I
L
V
P
G
L
L
V
A
Y
C
H
R
F
D
Rat
Rattus norvegicus
Q5PQL3
577
63718
V422
I
L
V
P
G
L
L
V
A
Y
C
H
R
F
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507224
648
71872
S423
R
F
D
V
Q
T
G
S
S
S
I
Y
Y
V
S
Chicken
Gallus gallus
Q5F383
596
66378
S437
R
F
D
I
Q
V
Q
S
S
R
V
Y
F
V
A
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_782326
512
56836
D364
L
S
L
L
F
V
Y
D
V
F
F
V
F
I
T
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
44.8
76.3
57.6
N.A.
78
77.1
N.A.
42.5
73.1
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
38.8
Protein Similarity:
100
57.7
77.6
62.9
N.A.
85.6
84.8
N.A.
60.4
81.7
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
56.2
P-Site Identity:
100
73.3
0
100
N.A.
0
0
N.A.
53.3
100
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
13.3
P-Site Similarity:
100
86.6
26.6
100
N.A.
20
20
N.A.
80
100
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
12
23
0
0
0
0
0
45
% A
% Cys:
0
0
0
0
0
0
12
0
12
0
23
0
0
0
0
% C
% Asp:
0
0
56
0
0
0
0
12
0
0
0
0
0
0
23
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
56
0
0
12
12
0
0
0
12
12
0
56
23
0
% F
% Gly:
0
0
0
0
23
0
12
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
23
0
0
0
% H
% Ile:
34
0
0
34
0
0
0
0
0
0
12
0
0
12
0
% I
% Lys:
0
0
0
0
0
0
12
0
0
0
0
0
0
0
0
% K
% Leu:
12
23
23
12
0
23
23
0
0
0
12
12
12
12
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
34
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
56
0
34
0
0
12
0
0
0
0
0
% Q
% Arg:
56
12
0
0
0
0
0
0
12
34
0
0
23
0
0
% R
% Ser:
0
12
0
0
0
0
0
56
45
12
0
0
0
0
12
% S
% Thr:
0
0
0
0
12
12
0
0
0
12
0
0
0
0
12
% T
% Val:
0
0
23
23
0
56
0
23
12
0
45
12
0
56
12
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
12
0
0
23
0
56
12
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _