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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SPPL2B
All Species:
1.82
Human Site:
S553
Identified Species:
5
UniProt:
Q8TCT7
Number Species:
8
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8TCT7
NP_001070706.1
592
64644
S553
P
A
E
Q
S
P
K
S
R
T
S
E
E
M
G
Chimpanzee
Pan troglodytes
XP_523673
684
74537
C601
P
E
D
R
S
D
S
C
E
G
W
S
D
A
H
Rhesus Macaque
Macaca mulatta
XP_001097918
495
54847
A457
L
M
Q
R
G
Q
P
A
L
L
Y
L
V
P
C
Dog
Lupus familis
XP_542189
880
94252
L681
P
H
G
Q
P
P
E
L
S
V
P
E
E
T
G
Cat
Felis silvestris
Mouse
Mus musculus
Q3TD49
578
63805
P535
S
E
E
L
A
K
S
P
L
S
T
E
E
A
G
Rat
Rattus norvegicus
Q5PQL3
577
63718
P534
G
E
E
L
A
Q
S
P
L
A
T
E
E
A
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507224
648
71872
T607
A
A
A
G
S
R
E
T
R
S
K
A
A
E
E
Chicken
Gallus gallus
Q5F383
596
66378
N558
A
A
E
E
P
A
D
N
D
T
K
T
E
Q
S
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_782326
512
56836
P474
I
L
M
Q
T
G
Q
P
A
L
L
Y
L
V
P
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
44.8
76.3
57.6
N.A.
78
77.1
N.A.
42.5
73.1
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
38.8
Protein Similarity:
100
57.7
77.6
62.9
N.A.
85.6
84.8
N.A.
60.4
81.7
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
56.2
P-Site Identity:
100
13.3
0
40
N.A.
26.6
26.6
N.A.
20
26.6
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
6.6
P-Site Similarity:
100
33.3
20
46.6
N.A.
46.6
40
N.A.
40
40
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
23
34
12
0
23
12
0
12
12
12
0
12
12
34
0
% A
% Cys:
0
0
0
0
0
0
0
12
0
0
0
0
0
0
12
% C
% Asp:
0
0
12
0
0
12
12
0
12
0
0
0
12
0
0
% D
% Glu:
0
34
45
12
0
0
23
0
12
0
0
45
56
12
12
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
12
0
12
12
12
12
0
0
0
12
0
0
0
0
45
% G
% His:
0
12
0
0
0
0
0
0
0
0
0
0
0
0
12
% H
% Ile:
12
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
12
12
0
0
0
23
0
0
0
0
% K
% Leu:
12
12
0
23
0
0
0
12
34
23
12
12
12
0
0
% L
% Met:
0
12
12
0
0
0
0
0
0
0
0
0
0
12
0
% M
% Asn:
0
0
0
0
0
0
0
12
0
0
0
0
0
0
0
% N
% Pro:
34
0
0
0
23
23
12
34
0
0
12
0
0
12
12
% P
% Gln:
0
0
12
34
0
23
12
0
0
0
0
0
0
12
0
% Q
% Arg:
0
0
0
23
0
12
0
0
23
0
0
0
0
0
0
% R
% Ser:
12
0
0
0
34
0
34
12
12
23
12
12
0
0
12
% S
% Thr:
0
0
0
0
12
0
0
12
0
23
23
12
0
12
0
% T
% Val:
0
0
0
0
0
0
0
0
0
12
0
0
12
12
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
12
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
12
12
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _