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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SPPL2B
All Species:
19.39
Human Site:
Y164
Identified Species:
53.33
UniProt:
Q8TCT7
Number Species:
8
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8TCT7
NP_001070706.1
592
64644
Y164
R
T
V
R
A
A
L
Y
A
P
K
E
P
V
L
Chimpanzee
Pan troglodytes
XP_523673
684
74537
Y176
A
V
V
R
V
A
M
Y
A
P
P
E
P
I
I
Rhesus Macaque
Macaca mulatta
XP_001097918
495
54847
C98
P
L
V
A
R
G
N
C
T
F
Y
E
K
V
R
Dog
Lupus familis
XP_542189
880
94252
Y292
R
A
V
R
A
A
L
Y
A
P
N
E
P
M
L
Cat
Felis silvestris
Mouse
Mus musculus
Q3TD49
578
63805
Y158
R
E
V
M
V
A
L
Y
A
P
S
E
P
V
M
Rat
Rattus norvegicus
Q5PQL3
577
63718
Y158
H
E
V
M
V
A
L
Y
A
P
S
E
P
V
M
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507224
648
71872
Y152
N
N
I
S
V
K
L
Y
S
P
P
S
P
E
F
Chicken
Gallus gallus
Q5F383
596
66378
Y160
R
S
V
K
G
A
M
Y
A
P
N
E
P
V
L
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_782326
512
56836
V115
L
V
I
S
E
T
G
V
T
A
P
S
F
N
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
44.8
76.3
57.6
N.A.
78
77.1
N.A.
42.5
73.1
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
38.8
Protein Similarity:
100
57.7
77.6
62.9
N.A.
85.6
84.8
N.A.
60.4
81.7
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
56.2
P-Site Identity:
100
53.3
20
80
N.A.
66.6
60
N.A.
26.6
66.6
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
0
P-Site Similarity:
100
73.3
20
86.6
N.A.
73.3
66.6
N.A.
40
86.6
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
12
12
0
12
23
67
0
0
67
12
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
12
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
23
0
0
12
0
0
0
0
0
0
78
0
12
12
% E
% Phe:
0
0
0
0
0
0
0
0
0
12
0
0
12
0
12
% F
% Gly:
0
0
0
0
12
12
12
0
0
0
0
0
0
0
0
% G
% His:
12
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
23
0
0
0
0
0
0
0
0
0
0
12
12
% I
% Lys:
0
0
0
12
0
12
0
0
0
0
12
0
12
0
0
% K
% Leu:
12
12
0
0
0
0
56
0
0
0
0
0
0
0
34
% L
% Met:
0
0
0
23
0
0
23
0
0
0
0
0
0
12
23
% M
% Asn:
12
12
0
0
0
0
12
0
0
0
23
0
0
12
0
% N
% Pro:
12
0
0
0
0
0
0
0
0
78
34
0
78
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
45
0
0
34
12
0
0
0
0
0
0
0
0
0
12
% R
% Ser:
0
12
0
23
0
0
0
0
12
0
23
23
0
0
0
% S
% Thr:
0
12
0
0
0
12
0
0
23
0
0
0
0
0
0
% T
% Val:
0
23
78
0
45
0
0
12
0
0
0
0
0
56
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
78
0
0
12
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _