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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SPPL2A
All Species:
28.79
Human Site:
S128
Identified Species:
57.58
UniProt:
Q8TCT8
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8TCT8
NP_116191.2
520
58143
S128
F
P
P
S
G
N
R
S
E
F
P
D
V
K
I
Chimpanzee
Pan troglodytes
XP_001169194
520
58154
S128
F
P
P
S
G
N
R
S
E
F
P
D
V
K
I
Rhesus Macaque
Macaca mulatta
XP_001097918
495
54847
T131
V
P
P
G
G
N
K
T
Q
Y
D
E
I
G
I
Dog
Lupus familis
XP_535476
570
63831
S159
F
P
P
S
G
N
K
S
E
F
H
D
V
K
I
Cat
Felis silvestris
Mouse
Mus musculus
Q9JJF9
523
58052
S131
I
P
S
S
R
N
K
S
T
F
Q
N
V
T
V
Rat
Rattus norvegicus
Q5PQL3
577
63718
T125
V
P
P
R
G
N
K
T
Q
Y
E
E
I
S
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507224
648
71872
T119
S
P
P
S
G
N
K
T
E
F
S
D
V
T
I
Chicken
Gallus gallus
Q5F383
596
66378
S127
V
P
P
G
G
N
R
S
Q
Y
E
E
I
D
I
Frog
Xenopus laevis
NP_001079884
606
68129
G124
Y
S
D
M
L
D
I
G
K
T
F
G
K
S
V
Zebra Danio
Brachydanio rerio
NP_001015067
564
62914
S133
T
P
P
S
G
N
K
S
Q
Y
E
E
I
G
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P49049
468
52775
I118
Q
K
I
N
S
T
I
I
S
Y
T
A
N
T
T
Sea Urchin
Strong. purpuratus
XP_782326
512
56836
F120
T
G
V
T
A
P
S
F
N
E
S
V
K
I
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
42.5
80.5
N.A.
79.7
42.4
N.A.
56.1
42.4
41.2
44.8
N.A.
N.A.
N.A.
21.7
37.6
Protein Similarity:
100
99.6
62.5
85.4
N.A.
89.2
62.7
N.A.
66.5
60.4
58.7
64.5
N.A.
N.A.
N.A.
37.3
58.4
P-Site Identity:
100
100
33.3
86.6
N.A.
40
33.3
N.A.
66.6
46.6
0
46.6
N.A.
N.A.
N.A.
0
0
P-Site Similarity:
100
100
73.3
93.3
N.A.
60
73.3
N.A.
80
73.3
26.6
80
N.A.
N.A.
N.A.
13.3
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
9
0
0
0
0
0
0
9
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
9
0
0
9
0
0
0
0
9
34
0
9
9
% D
% Glu:
0
0
0
0
0
0
0
0
34
9
25
34
0
0
0
% E
% Phe:
25
0
0
0
0
0
0
9
0
42
9
0
0
0
0
% F
% Gly:
0
9
0
17
67
0
0
9
0
0
0
9
0
17
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
9
0
0
0
0
% H
% Ile:
9
0
9
0
0
0
17
9
0
0
0
0
34
9
67
% I
% Lys:
0
9
0
0
0
0
50
0
9
0
0
0
17
25
0
% K
% Leu:
0
0
0
0
9
0
0
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
9
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
9
0
75
0
0
9
0
0
9
9
0
0
% N
% Pro:
0
75
67
0
0
9
0
0
0
0
17
0
0
0
0
% P
% Gln:
9
0
0
0
0
0
0
0
34
0
9
0
0
0
0
% Q
% Arg:
0
0
0
9
9
0
25
0
0
0
0
0
0
0
0
% R
% Ser:
9
9
9
50
9
0
9
50
9
0
17
0
0
17
0
% S
% Thr:
17
0
0
9
0
9
0
25
9
9
9
0
0
25
9
% T
% Val:
25
0
9
0
0
0
0
0
0
0
0
9
42
0
17
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
9
0
0
0
0
0
0
0
0
42
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _