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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SPPL2A
All Species:
8.48
Human Site:
S94
Identified Species:
16.97
UniProt:
Q8TCT8
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.27
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8TCT8
NP_116191.2
520
58143
S94
A
V
V
V
P
W
G
S
C
H
F
L
E
K
A
Chimpanzee
Pan troglodytes
XP_001169194
520
58154
S94
A
V
V
V
P
W
G
S
C
H
F
L
E
K
A
Rhesus Macaque
Macaca mulatta
XP_001097918
495
54847
N97
I
P
L
V
A
R
G
N
C
T
F
Y
E
K
V
Dog
Lupus familis
XP_535476
570
63831
T125
A
V
V
V
K
W
G
T
C
H
I
L
E
K
A
Cat
Felis silvestris
Mouse
Mus musculus
Q9JJF9
523
58052
P97
A
V
V
V
H
W
G
P
C
H
F
L
E
K
A
Rat
Rattus norvegicus
Q5PQL3
577
63718
R99
C
T
F
Y
E
K
V
R
L
A
Q
G
S
G
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507224
648
71872
I94
L
F
L
E
K
A
R
I
A
Q
S
R
G
A
K
Chicken
Gallus gallus
Q5F383
596
66378
R101
C
T
F
Y
E
K
V
R
L
A
Q
I
N
G
A
Frog
Xenopus laevis
NP_001079884
606
68129
L95
L
I
V
S
R
E
T
L
V
P
P
G
G
N
Q
Zebra Danio
Brachydanio rerio
NP_001015067
564
62914
N99
I
P
M
V
M
R
G
N
C
T
F
Y
E
K
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P49049
468
52775
F93
F
K
P
A
A
E
R
F
L
W
V
A
R
V
F
Sea Urchin
Strong. purpuratus
XP_782326
512
56836
K95
G
N
C
T
F
T
E
K
G
V
H
A
Q
Q
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
42.5
80.5
N.A.
79.7
42.4
N.A.
56.1
42.4
41.2
44.8
N.A.
N.A.
N.A.
21.7
37.6
Protein Similarity:
100
99.6
62.5
85.4
N.A.
89.2
62.7
N.A.
66.5
60.4
58.7
64.5
N.A.
N.A.
N.A.
37.3
58.4
P-Site Identity:
100
100
40
80
N.A.
86.6
6.6
N.A.
0
6.6
6.6
40
N.A.
N.A.
N.A.
0
6.6
P-Site Similarity:
100
100
53.3
86.6
N.A.
86.6
6.6
N.A.
6.6
13.3
13.3
53.3
N.A.
N.A.
N.A.
0
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
34
0
0
9
17
9
0
0
9
17
0
17
0
9
59
% A
% Cys:
17
0
9
0
0
0
0
0
50
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
9
17
17
9
0
0
0
0
0
50
0
0
% E
% Phe:
9
9
17
0
9
0
0
9
0
0
42
0
0
0
9
% F
% Gly:
9
0
0
0
0
0
50
0
9
0
0
17
17
17
0
% G
% His:
0
0
0
0
9
0
0
0
0
34
9
0
0
0
0
% H
% Ile:
17
9
0
0
0
0
0
9
0
0
9
9
0
0
0
% I
% Lys:
0
9
0
0
17
17
0
9
0
0
0
0
0
50
9
% K
% Leu:
17
0
17
0
0
0
0
9
25
0
0
34
0
0
0
% L
% Met:
0
0
9
0
9
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
9
0
0
0
0
0
17
0
0
0
0
9
9
0
% N
% Pro:
0
17
9
0
17
0
0
9
0
9
9
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
9
17
0
9
9
9
% Q
% Arg:
0
0
0
0
9
17
17
17
0
0
0
9
9
0
0
% R
% Ser:
0
0
0
9
0
0
0
17
0
0
9
0
9
0
0
% S
% Thr:
0
17
0
9
0
9
9
9
0
17
0
0
0
0
0
% T
% Val:
0
34
42
50
0
0
17
0
9
9
9
0
0
9
17
% V
% Trp:
0
0
0
0
0
34
0
0
0
9
0
0
0
0
0
% W
% Tyr:
0
0
0
17
0
0
0
0
0
0
0
17
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _