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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SPPL2A All Species: 21.21
Human Site: T151 Identified Species: 42.42
UniProt: Q8TCT8 Number Species: 11
    Phosphosite Substitution
    Charge Score: -0.18
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8TCT8 NP_116191.2 520 58143 T151 D F R D M N Q T L G D N I T V
Chimpanzee Pan troglodytes XP_001169194 520 58154 T151 D F R D M N Q T L G D N I T V
Rhesus Macaque Macaca mulatta XP_001097918 495 54847 R154 D M L D I F R R F G R M V R V
Dog Lupus familis XP_535476 570 63831 T182 D F I D M K Q T L G D N I T V
Cat Felis silvestris
Mouse Mus musculus Q9JJF9 523 58052 T154 D F K D M K E T L G D D I T V
Rat Rattus norvegicus Q5PQL3 577 63718 R148 D L Q D I F R R F G H E V M V
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001507224 648 71872 T142 D V E N M Q Q T F G N N I S V
Chicken Gallus gallus Q5F383 596 66378 S150 D M L D I V K S F G R S V K G
Frog Xenopus laevis NP_001079884 606 68129 M147 E P V L D Y N M V I I F L M A
Zebra Danio Brachydanio rerio NP_001015067 564 62914 T156 D M L D I S K T F G E K R Q V
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans P49049 468 52775 I141 L L R L A S R I P Q E R V P E
Sea Urchin Strong. purpuratus XP_782326 512 56836 N143 K D F Q D L T N Q G P S P E V
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.6 42.5 80.5 N.A. 79.7 42.4 N.A. 56.1 42.4 41.2 44.8 N.A. N.A. N.A. 21.7 37.6
Protein Similarity: 100 99.6 62.5 85.4 N.A. 89.2 62.7 N.A. 66.5 60.4 58.7 64.5 N.A. N.A. N.A. 37.3 58.4
P-Site Identity: 100 100 26.6 86.6 N.A. 73.3 26.6 N.A. 53.3 20 0 33.3 N.A. N.A. N.A. 6.6 13.3
P-Site Similarity: 100 100 46.6 86.6 N.A. 93.3 53.3 N.A. 73.3 53.3 20 60 N.A. N.A. N.A. 33.3 20
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 9 0 0 0 0 0 0 0 0 0 9 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 75 9 0 67 17 0 0 0 0 0 34 9 0 0 0 % D
% Glu: 9 0 9 0 0 0 9 0 0 0 17 9 0 9 9 % E
% Phe: 0 34 9 0 0 17 0 0 42 0 0 9 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 84 0 0 0 0 9 % G
% His: 0 0 0 0 0 0 0 0 0 0 9 0 0 0 0 % H
% Ile: 0 0 9 0 34 0 0 9 0 9 9 0 42 0 0 % I
% Lys: 9 0 9 0 0 17 17 0 0 0 0 9 0 9 0 % K
% Leu: 9 17 25 17 0 9 0 0 34 0 0 0 9 0 0 % L
% Met: 0 25 0 0 42 0 0 9 0 0 0 9 0 17 0 % M
% Asn: 0 0 0 9 0 17 9 9 0 0 9 34 0 0 0 % N
% Pro: 0 9 0 0 0 0 0 0 9 0 9 0 9 9 0 % P
% Gln: 0 0 9 9 0 9 34 0 9 9 0 0 0 9 0 % Q
% Arg: 0 0 25 0 0 0 25 17 0 0 17 9 9 9 0 % R
% Ser: 0 0 0 0 0 17 0 9 0 0 0 17 0 9 0 % S
% Thr: 0 0 0 0 0 0 9 50 0 0 0 0 0 34 0 % T
% Val: 0 9 9 0 0 9 0 0 9 0 0 0 34 0 75 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 9 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _