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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SPPL2A
All Species:
21.21
Human Site:
T151
Identified Species:
42.42
UniProt:
Q8TCT8
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.18
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8TCT8
NP_116191.2
520
58143
T151
D
F
R
D
M
N
Q
T
L
G
D
N
I
T
V
Chimpanzee
Pan troglodytes
XP_001169194
520
58154
T151
D
F
R
D
M
N
Q
T
L
G
D
N
I
T
V
Rhesus Macaque
Macaca mulatta
XP_001097918
495
54847
R154
D
M
L
D
I
F
R
R
F
G
R
M
V
R
V
Dog
Lupus familis
XP_535476
570
63831
T182
D
F
I
D
M
K
Q
T
L
G
D
N
I
T
V
Cat
Felis silvestris
Mouse
Mus musculus
Q9JJF9
523
58052
T154
D
F
K
D
M
K
E
T
L
G
D
D
I
T
V
Rat
Rattus norvegicus
Q5PQL3
577
63718
R148
D
L
Q
D
I
F
R
R
F
G
H
E
V
M
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507224
648
71872
T142
D
V
E
N
M
Q
Q
T
F
G
N
N
I
S
V
Chicken
Gallus gallus
Q5F383
596
66378
S150
D
M
L
D
I
V
K
S
F
G
R
S
V
K
G
Frog
Xenopus laevis
NP_001079884
606
68129
M147
E
P
V
L
D
Y
N
M
V
I
I
F
L
M
A
Zebra Danio
Brachydanio rerio
NP_001015067
564
62914
T156
D
M
L
D
I
S
K
T
F
G
E
K
R
Q
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P49049
468
52775
I141
L
L
R
L
A
S
R
I
P
Q
E
R
V
P
E
Sea Urchin
Strong. purpuratus
XP_782326
512
56836
N143
K
D
F
Q
D
L
T
N
Q
G
P
S
P
E
V
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
42.5
80.5
N.A.
79.7
42.4
N.A.
56.1
42.4
41.2
44.8
N.A.
N.A.
N.A.
21.7
37.6
Protein Similarity:
100
99.6
62.5
85.4
N.A.
89.2
62.7
N.A.
66.5
60.4
58.7
64.5
N.A.
N.A.
N.A.
37.3
58.4
P-Site Identity:
100
100
26.6
86.6
N.A.
73.3
26.6
N.A.
53.3
20
0
33.3
N.A.
N.A.
N.A.
6.6
13.3
P-Site Similarity:
100
100
46.6
86.6
N.A.
93.3
53.3
N.A.
73.3
53.3
20
60
N.A.
N.A.
N.A.
33.3
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
9
0
0
0
0
0
0
0
0
0
9
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
75
9
0
67
17
0
0
0
0
0
34
9
0
0
0
% D
% Glu:
9
0
9
0
0
0
9
0
0
0
17
9
0
9
9
% E
% Phe:
0
34
9
0
0
17
0
0
42
0
0
9
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
84
0
0
0
0
9
% G
% His:
0
0
0
0
0
0
0
0
0
0
9
0
0
0
0
% H
% Ile:
0
0
9
0
34
0
0
9
0
9
9
0
42
0
0
% I
% Lys:
9
0
9
0
0
17
17
0
0
0
0
9
0
9
0
% K
% Leu:
9
17
25
17
0
9
0
0
34
0
0
0
9
0
0
% L
% Met:
0
25
0
0
42
0
0
9
0
0
0
9
0
17
0
% M
% Asn:
0
0
0
9
0
17
9
9
0
0
9
34
0
0
0
% N
% Pro:
0
9
0
0
0
0
0
0
9
0
9
0
9
9
0
% P
% Gln:
0
0
9
9
0
9
34
0
9
9
0
0
0
9
0
% Q
% Arg:
0
0
25
0
0
0
25
17
0
0
17
9
9
9
0
% R
% Ser:
0
0
0
0
0
17
0
9
0
0
0
17
0
9
0
% S
% Thr:
0
0
0
0
0
0
9
50
0
0
0
0
0
34
0
% T
% Val:
0
9
9
0
0
9
0
0
9
0
0
0
34
0
75
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
9
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _