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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SPPL2A
All Species:
4.55
Human Site:
T203
Identified Species:
9.09
UniProt:
Q8TCT8
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.36
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8TCT8
NP_116191.2
520
58143
T203
E
N
L
K
A
V
T
T
E
D
R
E
M
R
K
Chimpanzee
Pan troglodytes
XP_001169194
520
58154
T203
E
N
L
K
A
V
T
T
E
D
R
E
M
R
K
Rhesus Macaque
Macaca mulatta
XP_001097918
495
54847
K206
K
K
R
Y
M
K
H
K
R
D
D
G
P
E
K
Dog
Lupus familis
XP_535476
570
63831
N234
E
S
M
K
A
V
T
N
T
E
D
R
E
T
R
Cat
Felis silvestris
Mouse
Mus musculus
Q9JJF9
523
58052
D206
E
N
M
K
S
V
E
D
A
E
D
R
E
T
R
Rat
Rattus norvegicus
Q5PQL3
577
63718
R200
K
K
Y
M
K
H
K
R
D
D
V
P
E
K
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507224
648
71872
N194
E
D
M
K
A
A
T
N
P
E
E
R
E
T
R
Chicken
Gallus gallus
Q5F383
596
66378
K202
K
E
R
Y
M
K
H
K
R
D
D
G
A
E
K
Frog
Xenopus laevis
NP_001079884
606
68129
I199
V
D
V
T
P
I
M
I
C
V
F
V
V
M
C
Zebra Danio
Brachydanio rerio
NP_001015067
564
62914
K208
K
K
R
Y
M
K
H
K
R
D
D
G
A
E
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P49049
468
52775
V193
A
S
L
L
K
P
F
V
T
A
F
L
K
K
M
Sea Urchin
Strong. purpuratus
XP_782326
512
56836
R195
K
Q
H
K
R
E
K
R
H
E
R
R
D
G
Q
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
42.5
80.5
N.A.
79.7
42.4
N.A.
56.1
42.4
41.2
44.8
N.A.
N.A.
N.A.
21.7
37.6
Protein Similarity:
100
99.6
62.5
85.4
N.A.
89.2
62.7
N.A.
66.5
60.4
58.7
64.5
N.A.
N.A.
N.A.
37.3
58.4
P-Site Identity:
100
100
13.3
33.3
N.A.
26.6
6.6
N.A.
26.6
13.3
0
13.3
N.A.
N.A.
N.A.
6.6
13.3
P-Site Similarity:
100
100
20
60
N.A.
53.3
33.3
N.A.
53.3
20
26.6
20
N.A.
N.A.
N.A.
20
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
0
0
0
34
9
0
0
9
9
0
0
17
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
9
0
0
0
0
0
9
% C
% Asp:
0
17
0
0
0
0
0
9
9
50
42
0
9
0
0
% D
% Glu:
42
9
0
0
0
9
9
0
17
34
9
17
34
25
0
% E
% Phe:
0
0
0
0
0
0
9
0
0
0
17
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
25
0
9
0
% G
% His:
0
0
9
0
0
9
25
0
9
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
9
0
9
0
0
0
0
0
0
0
% I
% Lys:
42
25
0
50
17
25
17
25
0
0
0
0
9
17
42
% K
% Leu:
0
0
25
9
0
0
0
0
0
0
0
9
0
0
0
% L
% Met:
0
0
25
9
25
0
9
0
0
0
0
0
17
9
9
% M
% Asn:
0
25
0
0
0
0
0
17
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
9
9
0
0
9
0
0
9
9
0
0
% P
% Gln:
0
9
0
0
0
0
0
0
0
0
0
0
0
0
17
% Q
% Arg:
0
0
25
0
9
0
0
17
25
0
25
34
0
17
25
% R
% Ser:
0
17
0
0
9
0
0
0
0
0
0
0
0
0
0
% S
% Thr:
0
0
0
9
0
0
34
17
17
0
0
0
0
25
0
% T
% Val:
9
0
9
0
0
34
0
9
0
9
9
9
9
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
9
25
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _