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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SPPL2A
All Species:
13.64
Human Site:
T430
Identified Species:
27.27
UniProt:
Q8TCT8
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8TCT8
NP_116191.2
520
58143
T430
C
R
R
F
D
V
Q
T
G
S
S
Y
I
Y
Y
Chimpanzee
Pan troglodytes
XP_001169194
520
58154
T430
C
R
R
F
D
V
Q
T
G
S
S
Y
I
Y
Y
Rhesus Macaque
Macaca mulatta
XP_001097918
495
54847
C405
H
H
P
V
S
L
L
C
V
P
P
P
G
L
L
Dog
Lupus familis
XP_535476
570
63831
T480
C
R
R
F
D
V
Q
T
G
S
S
S
I
Y
Y
Cat
Felis silvestris
Mouse
Mus musculus
Q9JJF9
523
58052
Q433
Y
C
R
R
F
D
V
Q
T
G
S
S
I
Y
Y
Rat
Rattus norvegicus
Q5PQL3
577
63718
V432
C
H
R
F
D
I
Q
V
Q
S
S
R
I
Y
F
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507224
648
71872
T421
C
R
R
F
D
V
Q
T
G
S
S
S
I
Y
Y
Chicken
Gallus gallus
Q5F383
596
66378
V435
C
H
R
F
D
I
Q
V
Q
S
S
R
V
Y
F
Frog
Xenopus laevis
NP_001079884
606
68129
V412
C
H
R
F
D
I
Q
V
Q
S
S
R
I
Y
F
Zebra Danio
Brachydanio rerio
NP_001015067
564
62914
M441
C
H
R
F
D
I
L
M
Q
T
S
Q
I
Y
F
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P49049
468
52775
Q382
T
A
E
S
K
A
P
Q
G
S
L
K
G
R
Y
Sea Urchin
Strong. purpuratus
XP_782326
512
56836
S411
R
L
C
H
S
A
F
S
V
C
N
V
Y
S
M
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
42.5
80.5
N.A.
79.7
42.4
N.A.
56.1
42.4
41.2
44.8
N.A.
N.A.
N.A.
21.7
37.6
Protein Similarity:
100
99.6
62.5
85.4
N.A.
89.2
62.7
N.A.
66.5
60.4
58.7
64.5
N.A.
N.A.
N.A.
37.3
58.4
P-Site Identity:
100
100
0
93.3
N.A.
33.3
60
N.A.
93.3
53.3
60
46.6
N.A.
N.A.
N.A.
20
0
P-Site Similarity:
100
100
6.6
93.3
N.A.
33.3
73.3
N.A.
93.3
73.3
73.3
66.6
N.A.
N.A.
N.A.
20
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
9
0
0
0
17
0
0
0
0
0
0
0
0
0
% A
% Cys:
67
9
9
0
0
0
0
9
0
9
0
0
0
0
0
% C
% Asp:
0
0
0
0
67
9
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
9
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
67
9
0
9
0
0
0
0
0
0
0
34
% F
% Gly:
0
0
0
0
0
0
0
0
42
9
0
0
17
0
0
% G
% His:
9
42
0
9
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
34
0
0
0
0
0
0
67
0
0
% I
% Lys:
0
0
0
0
9
0
0
0
0
0
0
9
0
0
0
% K
% Leu:
0
9
0
0
0
9
17
0
0
0
9
0
0
9
9
% L
% Met:
0
0
0
0
0
0
0
9
0
0
0
0
0
0
9
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
9
0
0
0
0
% N
% Pro:
0
0
9
0
0
0
9
0
0
9
9
9
0
0
0
% P
% Gln:
0
0
0
0
0
0
59
17
34
0
0
9
0
0
0
% Q
% Arg:
9
34
75
9
0
0
0
0
0
0
0
25
0
9
0
% R
% Ser:
0
0
0
9
17
0
0
9
0
67
75
25
0
9
0
% S
% Thr:
9
0
0
0
0
0
0
34
9
9
0
0
0
0
0
% T
% Val:
0
0
0
9
0
34
9
25
17
0
0
9
9
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
9
0
0
0
0
0
0
0
0
0
0
17
9
75
50
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _