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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SPPL2A All Species: 14.24
Human Site: T50 Identified Species: 28.48
UniProt: Q8TCT8 Number Species: 11
    Phosphosite Substitution
    Charge Score: -0.18
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8TCT8 NP_116191.2 520 58143 T50 M L Y N P Y W T A L P S T L E
Chimpanzee Pan troglodytes XP_001169194 520 58154 T50 M L Y N P Y W T A L P S T L E
Rhesus Macaque Macaca mulatta XP_001097918 495 54847 A53 I L Y N P Q W A H L P H D L S
Dog Lupus familis XP_535476 570 63831 T81 M L Y N P Q W T S L P N T L E
Cat Felis silvestris
Mouse Mus musculus Q9JJF9 523 58052 T53 M Y Y N N N W T R L P S S L E
Rat Rattus norvegicus Q5PQL3 577 63718 K55 H L P H D L N K V S L L K L R
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001507224 648 71872 A50 F P D S L E N A T S I A L E N
Chicken Gallus gallus Q5F383 596 66378 K57 H L P H D L G K A S L L Q L Q
Frog Xenopus laevis NP_001079884 606 68129 S51 E I A L C L P S D V P E G G F
Zebra Danio Brachydanio rerio NP_001015067 564 62914 A55 I F F N S Q W A R L P Q D L S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans P49049 468 52775 I49 S I R S A Q Y I R T N I D K K
Sea Urchin Strong. purpuratus XP_782326 512 56836 T51 S K Q Y K L P T K L D Q S A Y
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.6 42.5 80.5 N.A. 79.7 42.4 N.A. 56.1 42.4 41.2 44.8 N.A. N.A. N.A. 21.7 37.6
Protein Similarity: 100 99.6 62.5 85.4 N.A. 89.2 62.7 N.A. 66.5 60.4 58.7 64.5 N.A. N.A. N.A. 37.3 58.4
P-Site Identity: 100 100 53.3 80 N.A. 66.6 13.3 N.A. 0 20 6.6 33.3 N.A. N.A. N.A. 0 13.3
P-Site Similarity: 100 100 60 93.3 N.A. 73.3 20 N.A. 13.3 33.3 26.6 46.6 N.A. N.A. N.A. 26.6 20
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 9 0 9 0 0 25 25 0 0 9 0 9 0 % A
% Cys: 0 0 0 0 9 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 9 0 17 0 0 0 9 0 9 0 25 0 0 % D
% Glu: 9 0 0 0 0 9 0 0 0 0 0 9 0 9 34 % E
% Phe: 9 9 9 0 0 0 0 0 0 0 0 0 0 0 9 % F
% Gly: 0 0 0 0 0 0 9 0 0 0 0 0 9 9 0 % G
% His: 17 0 0 17 0 0 0 0 9 0 0 9 0 0 0 % H
% Ile: 17 17 0 0 0 0 0 9 0 0 9 9 0 0 0 % I
% Lys: 0 9 0 0 9 0 0 17 9 0 0 0 9 9 9 % K
% Leu: 0 50 0 9 9 34 0 0 0 59 17 17 9 67 0 % L
% Met: 34 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 50 9 9 17 0 0 0 9 9 0 0 9 % N
% Pro: 0 9 17 0 34 0 17 0 0 0 59 0 0 0 0 % P
% Gln: 0 0 9 0 0 34 0 0 0 0 0 17 9 0 9 % Q
% Arg: 0 0 9 0 0 0 0 0 25 0 0 0 0 0 9 % R
% Ser: 17 0 0 17 9 0 0 9 9 25 0 25 17 0 17 % S
% Thr: 0 0 0 0 0 0 0 42 9 9 0 0 25 0 0 % T
% Val: 0 0 0 0 0 0 0 0 9 9 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 50 0 0 0 0 0 0 0 0 % W
% Tyr: 0 9 42 9 0 17 9 0 0 0 0 0 0 0 9 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _