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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SPPL2A
All Species:
29.39
Human Site:
Y161
Identified Species:
58.79
UniProt:
Q8TCT8
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8TCT8
NP_116191.2
520
58143
Y161
D
N
I
T
V
K
M
Y
S
P
S
W
P
N
F
Chimpanzee
Pan troglodytes
XP_001169194
520
58154
Y161
D
N
I
T
V
K
M
Y
S
P
S
W
P
N
F
Rhesus Macaque
Macaca mulatta
XP_001097918
495
54847
Y164
R
M
V
R
V
A
L
Y
A
P
H
E
P
V
L
Dog
Lupus familis
XP_535476
570
63831
Y192
D
N
I
T
V
K
M
Y
S
P
S
W
P
N
F
Cat
Felis silvestris
Mouse
Mus musculus
Q9JJF9
523
58052
Y164
D
D
I
T
V
K
M
Y
S
P
S
W
P
N
F
Rat
Rattus norvegicus
Q5PQL3
577
63718
Y158
H
E
V
M
V
A
L
Y
A
P
S
E
P
V
M
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507224
648
71872
Y152
N
N
I
S
V
K
L
Y
S
P
P
S
P
E
F
Chicken
Gallus gallus
Q5F383
596
66378
Y160
R
S
V
K
G
A
M
Y
A
P
N
E
P
V
L
Frog
Xenopus laevis
NP_001079884
606
68129
T157
I
F
L
M
A
V
G
T
V
A
V
G
G
Y
W
Zebra Danio
Brachydanio rerio
NP_001015067
564
62914
Y166
E
K
R
Q
V
A
M
Y
A
P
N
E
P
V
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P49049
468
52775
Q151
E
R
V
P
E
A
I
Q
N
A
A
T
Y
A
Y
Sea Urchin
Strong. purpuratus
XP_782326
512
56836
Y153
P
S
P
E
V
A
F
Y
S
P
E
P
P
E
W
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
42.5
80.5
N.A.
79.7
42.4
N.A.
56.1
42.4
41.2
44.8
N.A.
N.A.
N.A.
21.7
37.6
Protein Similarity:
100
99.6
62.5
85.4
N.A.
89.2
62.7
N.A.
66.5
60.4
58.7
64.5
N.A.
N.A.
N.A.
37.3
58.4
P-Site Identity:
100
100
26.6
100
N.A.
93.3
33.3
N.A.
60
26.6
0
33.3
N.A.
N.A.
N.A.
0
33.3
P-Site Similarity:
100
100
46.6
100
N.A.
100
53.3
N.A.
80
53.3
13.3
53.3
N.A.
N.A.
N.A.
40
46.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
9
50
0
0
34
17
9
0
0
9
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
34
9
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
17
9
0
9
9
0
0
0
0
0
9
34
0
17
0
% E
% Phe:
0
9
0
0
0
0
9
0
0
0
0
0
0
0
42
% F
% Gly:
0
0
0
0
9
0
9
0
0
0
0
9
9
0
0
% G
% His:
9
0
0
0
0
0
0
0
0
0
9
0
0
0
0
% H
% Ile:
9
0
42
0
0
0
9
0
0
0
0
0
0
0
0
% I
% Lys:
0
9
0
9
0
42
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
9
0
0
0
25
0
0
0
0
0
0
0
17
% L
% Met:
0
9
0
17
0
0
50
0
0
0
0
0
0
0
9
% M
% Asn:
9
34
0
0
0
0
0
0
9
0
17
0
0
34
0
% N
% Pro:
9
0
9
9
0
0
0
0
0
84
9
9
84
0
0
% P
% Gln:
0
0
0
9
0
0
0
9
0
0
0
0
0
0
0
% Q
% Arg:
17
9
9
9
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
17
0
9
0
0
0
0
50
0
42
9
0
0
0
% S
% Thr:
0
0
0
34
0
0
0
9
0
0
0
9
0
0
0
% T
% Val:
0
0
34
0
75
9
0
0
9
0
9
0
0
34
9
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
34
0
0
17
% W
% Tyr:
0
0
0
0
0
0
0
84
0
0
0
0
9
9
9
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _