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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SPPL2A
All Species:
9.7
Human Site:
Y215
Identified Species:
19.39
UniProt:
Q8TCT8
Number Species:
11
Phosphosite Substitution
Charge Score:
0.27
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8TCT8
NP_116191.2
520
58143
Y215
M
R
K
K
K
E
E
Y
L
T
F
S
P
L
T
Chimpanzee
Pan troglodytes
XP_001169194
520
58154
Y215
M
R
K
K
K
E
E
Y
L
T
F
S
P
L
T
Rhesus Macaque
Macaca mulatta
XP_001097918
495
54847
A218
P
E
K
Q
E
D
E
A
V
D
V
T
P
V
M
Dog
Lupus familis
XP_535476
570
63831
E246
E
T
R
R
K
K
D
E
Y
L
T
F
S
P
L
Cat
Felis silvestris
Mouse
Mus musculus
Q9JJF9
523
58052
D218
E
T
R
K
K
K
D
D
Y
L
T
F
S
P
L
Rat
Rattus norvegicus
Q5PQL3
577
63718
V212
E
K
Q
E
D
E
A
V
D
V
T
P
V
M
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507224
648
71872
E206
E
T
R
R
K
K
E
E
N
V
T
F
T
P
L
Chicken
Gallus gallus
Q5F383
596
66378
T214
A
E
K
H
E
D
E
T
V
D
V
T
P
I
M
Frog
Xenopus laevis
NP_001079884
606
68129
V211
V
M
C
C
S
M
L
V
L
L
Y
Y
F
Y
D
Zebra Danio
Brachydanio rerio
NP_001015067
564
62914
T220
A
E
K
Q
D
E
E
T
V
D
V
T
P
I
M
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P49049
468
52775
S205
K
K
M
P
L
V
P
S
F
L
R
F
N
A
P
Sea Urchin
Strong. purpuratus
XP_782326
512
56836
N207
D
G
Q
G
H
Y
Q
N
V
N
S
G
D
S
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
42.5
80.5
N.A.
79.7
42.4
N.A.
56.1
42.4
41.2
44.8
N.A.
N.A.
N.A.
21.7
37.6
Protein Similarity:
100
99.6
62.5
85.4
N.A.
89.2
62.7
N.A.
66.5
60.4
58.7
64.5
N.A.
N.A.
N.A.
37.3
58.4
P-Site Identity:
100
100
20
6.6
N.A.
13.3
6.6
N.A.
13.3
20
6.6
26.6
N.A.
N.A.
N.A.
0
0
P-Site Similarity:
100
100
60
33.3
N.A.
33.3
33.3
N.A.
33.3
53.3
20
53.3
N.A.
N.A.
N.A.
6.6
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
17
0
0
0
0
0
9
9
0
0
0
0
0
9
0
% A
% Cys:
0
0
9
9
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
9
0
0
0
17
17
17
9
9
25
0
0
9
0
9
% D
% Glu:
34
25
0
9
17
34
50
17
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
9
0
17
34
9
0
0
% F
% Gly:
0
9
0
9
0
0
0
0
0
0
0
9
0
0
0
% G
% His:
0
0
0
9
9
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
17
9
% I
% Lys:
9
17
42
25
42
25
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
9
0
9
0
25
34
0
0
0
17
25
% L
% Met:
17
9
9
0
0
9
0
0
0
0
0
0
0
9
25
% M
% Asn:
0
0
0
0
0
0
0
9
9
9
0
0
9
0
0
% N
% Pro:
9
0
0
9
0
0
9
0
0
0
0
9
42
25
9
% P
% Gln:
0
0
17
17
0
0
9
0
0
0
0
0
0
0
0
% Q
% Arg:
0
17
25
17
0
0
0
0
0
0
9
0
0
0
0
% R
% Ser:
0
0
0
0
9
0
0
9
0
0
9
17
17
9
9
% S
% Thr:
0
25
0
0
0
0
0
17
0
17
34
25
9
0
17
% T
% Val:
9
0
0
0
0
9
0
17
34
17
25
0
9
9
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
9
0
17
17
0
9
9
0
9
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _