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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SPPL2A
All Species:
16.97
Human Site:
Y41
Identified Species:
33.94
UniProt:
Q8TCT8
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8TCT8
NP_116191.2
520
58143
Y41
G
N
G
T
T
K
D
Y
C
M
L
Y
N
P
Y
Chimpanzee
Pan troglodytes
XP_001169194
520
58154
Y41
G
N
G
T
T
K
D
Y
C
M
L
Y
N
P
Y
Rhesus Macaque
Macaca mulatta
XP_001097918
495
54847
Y44
G
G
P
R
G
K
D
Y
C
I
L
Y
N
P
Q
Dog
Lupus familis
XP_535476
570
63831
Y72
K
L
L
P
S
K
D
Y
C
M
L
Y
N
P
Q
Cat
Felis silvestris
Mouse
Mus musculus
Q9JJF9
523
58052
Y44
V
S
S
L
S
K
D
Y
C
M
Y
Y
N
N
N
Rat
Rattus norvegicus
Q5PQL3
577
63718
W46
C
I
L
Y
N
P
Q
W
A
H
L
P
H
D
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507224
648
71872
T41
M
I
F
N
P
Q
W
T
T
F
P
D
S
L
E
Chicken
Gallus gallus
Q5F383
596
66378
W48
C
I
L
F
N
S
Q
W
A
H
L
P
H
D
L
Frog
Xenopus laevis
NP_001079884
606
68129
E42
G
L
L
Q
L
Q
N
E
T
E
I
A
L
C
L
Zebra Danio
Brachydanio rerio
NP_001015067
564
62914
Y46
G
N
S
K
G
K
D
Y
C
I
F
F
N
S
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P49049
468
52775
I40
M
S
I
L
C
I
I
I
G
S
I
R
S
A
Q
Sea Urchin
Strong. purpuratus
XP_782326
512
56836
Y42
S
R
E
Y
C
I
M
Y
D
S
K
Q
Y
K
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
42.5
80.5
N.A.
79.7
42.4
N.A.
56.1
42.4
41.2
44.8
N.A.
N.A.
N.A.
21.7
37.6
Protein Similarity:
100
99.6
62.5
85.4
N.A.
89.2
62.7
N.A.
66.5
60.4
58.7
64.5
N.A.
N.A.
N.A.
37.3
58.4
P-Site Identity:
100
100
60
60
N.A.
46.6
6.6
N.A.
0
6.6
6.6
46.6
N.A.
N.A.
N.A.
0
6.6
P-Site Similarity:
100
100
66.6
66.6
N.A.
60
20
N.A.
13.3
20
26.6
60
N.A.
N.A.
N.A.
20
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
17
0
0
9
0
9
0
% A
% Cys:
17
0
0
0
17
0
0
0
50
0
0
0
0
9
0
% C
% Asp:
0
0
0
0
0
0
50
0
9
0
0
9
0
17
0
% D
% Glu:
0
0
9
0
0
0
0
9
0
9
0
0
0
0
9
% E
% Phe:
0
0
9
9
0
0
0
0
0
9
9
9
0
0
0
% F
% Gly:
42
9
17
0
17
0
0
0
9
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
17
0
0
17
0
0
% H
% Ile:
0
25
9
0
0
17
9
9
0
17
17
0
0
0
0
% I
% Lys:
9
0
0
9
0
50
0
0
0
0
9
0
0
9
0
% K
% Leu:
0
17
34
17
9
0
0
0
0
0
50
0
9
9
34
% L
% Met:
17
0
0
0
0
0
9
0
0
34
0
0
0
0
0
% M
% Asn:
0
25
0
9
17
0
9
0
0
0
0
0
50
9
9
% N
% Pro:
0
0
9
9
9
9
0
0
0
0
9
17
0
34
0
% P
% Gln:
0
0
0
9
0
17
17
0
0
0
0
9
0
0
34
% Q
% Arg:
0
9
0
9
0
0
0
0
0
0
0
9
0
0
0
% R
% Ser:
9
17
17
0
17
9
0
0
0
17
0
0
17
9
0
% S
% Thr:
0
0
0
17
17
0
0
9
17
0
0
0
0
0
0
% T
% Val:
9
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
9
17
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
17
0
0
0
59
0
0
9
42
9
0
17
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _