KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SPPL2A
All Species:
13.94
Human Site:
Y495
Identified Species:
27.88
UniProt:
Q8TCT8
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8TCT8
NP_116191.2
520
58143
Y495
K
F
W
K
G
N
S
Y
Q
M
M
D
H
L
D
Chimpanzee
Pan troglodytes
XP_001169194
520
58154
Y495
K
F
W
K
G
N
S
Y
Q
M
M
D
H
L
D
Rhesus Macaque
Macaca mulatta
XP_001097918
495
54847
A471
C
T
L
V
T
S
C
A
V
A
L
W
R
R
E
Dog
Lupus familis
XP_535476
570
63831
Y545
K
F
W
K
G
S
G
Y
Q
V
M
D
H
L
D
Cat
Felis silvestris
Mouse
Mus musculus
Q9JJF9
523
58052
Y498
K
F
W
K
G
S
S
Y
Q
V
M
G
H
L
D
Rat
Rattus norvegicus
Q5PQL3
577
63718
T537
L
A
Q
S
P
L
A
T
E
E
A
G
A
T
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507224
648
71872
G621
E
S
G
D
I
K
Q
G
G
M
M
D
H
L
D
Chicken
Gallus gallus
Q5F383
596
66378
V567
T
K
T
E
Q
S
E
V
S
I
A
Q
S
E
E
Frog
Xenopus laevis
NP_001079884
606
68129
H507
E
K
T
E
D
Q
E
H
E
E
D
T
D
R
H
Zebra Danio
Brachydanio rerio
NP_001015067
564
62914
D527
Q
T
P
G
P
S
T
D
E
P
P
S
N
P
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P49049
468
52775
W444
R
G
E
L
S
A
L
W
N
Y
D
E
S
R
H
Sea Urchin
Strong. purpuratus
XP_782326
512
56836
V484
L
Y
L
V
P
C
T
V
L
S
T
L
A
V
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
42.5
80.5
N.A.
79.7
42.4
N.A.
56.1
42.4
41.2
44.8
N.A.
N.A.
N.A.
21.7
37.6
Protein Similarity:
100
99.6
62.5
85.4
N.A.
89.2
62.7
N.A.
66.5
60.4
58.7
64.5
N.A.
N.A.
N.A.
37.3
58.4
P-Site Identity:
100
100
0
80
N.A.
80
6.6
N.A.
40
0
0
0
N.A.
N.A.
N.A.
0
0
P-Site Similarity:
100
100
20
93.3
N.A.
93.3
20
N.A.
46.6
26.6
26.6
40
N.A.
N.A.
N.A.
20
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
9
0
0
0
9
9
9
0
9
17
0
17
0
9
% A
% Cys:
9
0
0
0
0
9
9
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
9
9
0
0
9
0
0
17
34
9
0
50
% D
% Glu:
17
0
9
17
0
0
17
0
25
17
0
9
0
9
25
% E
% Phe:
0
34
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
9
9
9
34
0
9
9
9
0
0
17
0
0
0
% G
% His:
0
0
0
0
0
0
0
9
0
0
0
0
42
0
17
% H
% Ile:
0
0
0
0
9
0
0
0
0
9
0
0
0
0
0
% I
% Lys:
34
17
0
34
0
9
0
0
0
0
0
0
0
0
0
% K
% Leu:
17
0
17
9
0
9
9
0
9
0
9
9
0
42
0
% L
% Met:
0
0
0
0
0
0
0
0
0
25
42
0
0
0
0
% M
% Asn:
0
0
0
0
0
17
0
0
9
0
0
0
9
0
0
% N
% Pro:
0
0
9
0
25
0
0
0
0
9
9
0
0
9
0
% P
% Gln:
9
0
9
0
9
9
9
0
34
0
0
9
0
0
0
% Q
% Arg:
9
0
0
0
0
0
0
0
0
0
0
0
9
25
0
% R
% Ser:
0
9
0
9
9
42
25
0
9
9
0
9
17
0
0
% S
% Thr:
9
17
17
0
9
0
17
9
0
0
9
9
0
9
0
% T
% Val:
0
0
0
17
0
0
0
17
9
17
0
0
0
9
0
% V
% Trp:
0
0
34
0
0
0
0
9
0
0
0
9
0
0
0
% W
% Tyr:
0
9
0
0
0
0
0
34
0
9
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _