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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ALMS1 All Species: 9.39
Human Site: S3196 Identified Species: 34.44
UniProt: Q8TCU4 Number Species: 6
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8TCU4 NP_055935.4 4167 460937 S3196 S A F S E K L S S D A V T Q I
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001105121 4171 460833 S3200 S A F S E K L S S D A V T Q I
Dog Lupus familis XP_533005 4146 460255 S3179 S A F P G K L S S D A V T Q I
Cat Felis silvestris
Mouse Mus musculus Q8K4E0 3251 360220 Q2368 G I L D P M A Q K P S R F A S
Rat Rattus norvegicus NP_001100074 2564 281531 G1681 F N L G R D Y G Y P V S E L N
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_420887 2322 257210 A1439 T L S P K Y P A K S R K S T S
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_690375 1912 209603 T1029 A L R E G F S T K P F T S I T
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. 93.1 67 N.A. 48.3 37.3 N.A. N.A. 21.5 N.A. 20.2 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 N.A. 95.7 76.7 N.A. 58.4 45.5 N.A. N.A. 34.5 N.A. 31.3 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 N.A. 100 86.6 N.A. 0 0 N.A. N.A. 0 N.A. 0 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 N.A. 100 86.6 N.A. 6.6 0 N.A. N.A. 26.6 N.A. 20 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 15 43 0 0 0 0 15 15 0 0 43 0 0 15 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 15 0 15 0 0 0 43 0 0 0 0 0 % D
% Glu: 0 0 0 15 29 0 0 0 0 0 0 0 15 0 0 % E
% Phe: 15 0 43 0 0 15 0 0 0 0 15 0 15 0 0 % F
% Gly: 15 0 0 15 29 0 0 15 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 15 0 0 0 0 0 0 0 0 0 0 0 15 43 % I
% Lys: 0 0 0 0 15 43 0 0 43 0 0 15 0 0 0 % K
% Leu: 0 29 29 0 0 0 43 0 0 0 0 0 0 15 0 % L
% Met: 0 0 0 0 0 15 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 15 0 0 0 0 0 0 0 0 0 0 0 0 15 % N
% Pro: 0 0 0 29 15 0 15 0 0 43 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 15 0 0 0 0 0 43 0 % Q
% Arg: 0 0 15 0 15 0 0 0 0 0 15 15 0 0 0 % R
% Ser: 43 0 15 29 0 0 15 43 43 15 15 15 29 0 29 % S
% Thr: 15 0 0 0 0 0 0 15 0 0 0 15 43 15 15 % T
% Val: 0 0 0 0 0 0 0 0 0 0 15 43 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 15 15 0 15 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _