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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PREX1 All Species: 18.79
Human Site: S323 Identified Species: 51.67
UniProt: Q8TCU6 Number Species: 8
    Phosphosite Substitution
    Charge Score: -0.38
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8TCU6 NP_065871.2 1659 186203 S323 R T K S I N G S L Y I F R G R
Chimpanzee Pan troglodytes XP_519798 1764 199053 R455 D G H R Y L F R G R I N T E V
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_543041 1633 183396 S319 R T K S I N G S L Y I F R G R
Cat Felis silvestris
Mouse Mus musculus Q69ZK0 1650 184917 S318 R T K S I N G S L Y I F R G R
Rat Rattus norvegicus NP_001129190 1646 184659 S318 R T K S I N G S L Y I F R G R
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506803 1633 183894 S303 D G T A D Y H S N G Y T V T N
Chicken Gallus gallus XP_417387 1627 183859 S304 R T K S I N G S L Y I F R G R
Frog Xenopus laevis NP_001083702 1639 186749 R302 N G S L Y I F R G R I N T E V
Zebra Danio Brachydanio rerio XP_699627 1622 184536 R304 N G P Q Y V F R G R I N T E V
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 54.9 N.A. 89.9 N.A. 90.4 90.3 N.A. 78.9 80.7 76.8 66.9 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 70.2 N.A. 93.1 N.A. 94.5 94.1 N.A. 85.9 88.4 87 80.8 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 6.6 N.A. 100 N.A. 100 100 N.A. 6.6 100 6.6 6.6 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 6.6 N.A. 100 N.A. 100 100 N.A. 13.3 100 6.6 6.6 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 12 0 0 0 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 23 0 0 0 12 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 0 0 34 0 % E
% Phe: 0 0 0 0 0 0 34 0 0 0 0 56 0 0 0 % F
% Gly: 0 45 0 0 0 0 56 0 34 12 0 0 0 56 0 % G
% His: 0 0 12 0 0 0 12 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 56 12 0 0 0 0 89 0 0 0 0 % I
% Lys: 0 0 56 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 0 0 12 0 12 0 0 56 0 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 23 0 0 0 0 56 0 0 12 0 0 34 0 0 12 % N
% Pro: 0 0 12 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 12 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 56 0 0 12 0 0 0 34 0 34 0 0 56 0 56 % R
% Ser: 0 0 12 56 0 0 0 67 0 0 0 0 0 0 0 % S
% Thr: 0 56 12 0 0 0 0 0 0 0 0 12 34 12 0 % T
% Val: 0 0 0 0 0 12 0 0 0 0 0 0 12 0 34 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 34 12 0 0 0 56 12 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _