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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: DYNC2LI1 All Species: 33.94
Human Site: S284 Identified Species: 62.22
UniProt: Q8TCX1 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8TCX1 NP_001012683.1 351 39625 S284 I G K L H A H S P M E L W K K
Chimpanzee Pan troglodytes XP_001142891 351 39644 S284 I G K L H A H S P M E L W K K
Rhesus Macaque Macaca mulatta XP_001107231 365 41489 S298 I G K L H A H S P M E L W K K
Dog Lupus familis XP_851613 348 39382 S281 I G K L H A H S P M D L W K K
Cat Felis silvestris
Mouse Mus musculus Q8K0T2 351 39451 S284 I G K L Q A H S P M E L W K K
Rat Rattus norvegicus Q6AY43 351 39651 S284 I G K L Q A H S P M E L W K K
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001513530 449 49836 T273 I G K L R V Q T P L E L W K E
Chicken Gallus gallus XP_419456 637 70733 T569 I G K M R A N T P L E L W K K
Frog Xenopus laevis
Zebra Danio Brachydanio rerio Q7SXY4 358 40170 N291 I G T L H A K N P F D L W K K
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_609289 368 41696 G305 A Q S V E R I G A T F G M E V
Honey Bee Apis mellifera XP_001121791 345 39466 A275 F P Q T R P S A M L D T I K Q
Nematode Worm Caenorhab. elegans NP_506683 370 42816 N294 M G A S S P F N L W R E S F I
Sea Urchin Strong. purpuratus XP_794270 363 40931 T291 L G R S N A R T P L D L W K Q
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98 87.6 90.8 N.A. 87.7 88.3 N.A. 51.4 37.2 N.A. 59.5 N.A. 31.5 32.7 32.9 49
Protein Similarity: 100 98.2 90.1 94.8 N.A. 93.7 94 N.A. 62.8 47.4 N.A. 74.5 N.A. 51 55.2 57 69.9
P-Site Identity: 100 100 100 93.3 N.A. 93.3 93.3 N.A. 60 66.6 N.A. 66.6 N.A. 0 6.6 6.6 40
P-Site Similarity: 100 100 100 100 N.A. 93.3 93.3 N.A. 80 93.3 N.A. 80 N.A. 13.3 40 20 86.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 0 8 0 0 70 0 8 8 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 31 0 0 0 0 % D
% Glu: 0 0 0 0 8 0 0 0 0 0 54 8 0 8 8 % E
% Phe: 8 0 0 0 0 0 8 0 0 8 8 0 0 8 0 % F
% Gly: 0 85 0 0 0 0 0 8 0 0 0 8 0 0 0 % G
% His: 0 0 0 0 39 0 47 0 0 0 0 0 0 0 0 % H
% Ile: 70 0 0 0 0 0 8 0 0 0 0 0 8 0 8 % I
% Lys: 0 0 62 0 0 0 8 0 0 0 0 0 0 85 62 % K
% Leu: 8 0 0 62 0 0 0 0 8 31 0 77 0 0 0 % L
% Met: 8 0 0 8 0 0 0 0 8 47 0 0 8 0 0 % M
% Asn: 0 0 0 0 8 0 8 16 0 0 0 0 0 0 0 % N
% Pro: 0 8 0 0 0 16 0 0 77 0 0 0 0 0 0 % P
% Gln: 0 8 8 0 16 0 8 0 0 0 0 0 0 0 16 % Q
% Arg: 0 0 8 0 24 8 8 0 0 0 8 0 0 0 0 % R
% Ser: 0 0 8 16 8 0 8 47 0 0 0 0 8 0 0 % S
% Thr: 0 0 8 8 0 0 0 24 0 8 0 8 0 0 0 % T
% Val: 0 0 0 8 0 8 0 0 0 0 0 0 0 0 8 % V
% Trp: 0 0 0 0 0 0 0 0 0 8 0 0 77 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _