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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MAPK15
All Species:
3.33
Human Site:
S392
Identified Species:
7.33
UniProt:
Q8TD08
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.2
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8TD08
NP_620590.2
544
59832
S392
G
P
R
P
R
P
Q
S
S
P
G
H
D
P
A
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_539201
559
60934
S399
K
P
G
R
R
P
Q
S
S
P
G
R
Q
G
A
Cat
Felis silvestris
Mouse
Mus musculus
Q80Y86
549
60660
R393
V
P
A
E
T
P
A
R
K
R
G
P
K
P
P
Rat
Rattus norvegicus
Q9Z2A6
547
60705
R393
A
E
T
P
A
R
K
R
G
P
K
P
Q
N
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_423954
600
66936
A417
K
S
H
R
V
P
T
A
P
P
L
K
Q
P
H
Frog
Xenopus laevis
P26696
361
41238
Y236
P
I
F
P
G
K
H
Y
L
D
Q
L
N
H
I
Zebra Danio
Brachydanio rerio
NP_001018581
524
58806
L393
V
K
P
P
S
H
L
L
R
L
V
K
R
N
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_392445
747
85295
H476
N
V
A
T
Q
Y
T
H
N
F
V
N
G
N
L
Nematode Worm
Caenorhab. elegans
Q11179
470
54020
I345
R
D
R
L
Y
E
M
I
D
E
K
K
A
S
F
Sea Urchin
Strong. purpuratus
XP_001203135
583
64666
A404
G
T
S
R
Q
R
P
A
A
A
V
G
P
G
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P14681
368
42674
G243
W
L
I
L
E
V
L
G
T
P
S
F
E
D
F
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
N.A.
71.5
N.A.
69.2
68.7
N.A.
N.A.
45.3
28.6
48.3
N.A.
N.A.
34.6
42.6
44.9
Protein Similarity:
100
N.A.
N.A.
77.8
N.A.
75.5
75.1
N.A.
N.A.
60
42
64.8
N.A.
N.A.
50.5
61.2
62.6
P-Site Identity:
100
N.A.
N.A.
60
N.A.
26.6
13.3
N.A.
N.A.
20
6.6
6.6
N.A.
N.A.
0
6.6
6.6
P-Site Similarity:
100
N.A.
N.A.
60
N.A.
26.6
20
N.A.
N.A.
26.6
13.3
6.6
N.A.
N.A.
20
6.6
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
29.7
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
42.8
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
0
19
0
10
0
10
19
10
10
0
0
10
0
19
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
10
0
0
0
0
0
0
10
10
0
0
10
10
0
% D
% Glu:
0
10
0
10
10
10
0
0
0
10
0
0
10
0
0
% E
% Phe:
0
0
10
0
0
0
0
0
0
10
0
10
0
0
19
% F
% Gly:
19
0
10
0
10
0
0
10
10
0
28
10
10
19
19
% G
% His:
0
0
10
0
0
10
10
10
0
0
0
10
0
10
10
% H
% Ile:
0
10
10
0
0
0
0
10
0
0
0
0
0
0
10
% I
% Lys:
19
10
0
0
0
10
10
0
10
0
19
28
10
0
0
% K
% Leu:
0
10
0
19
0
0
19
10
10
10
10
10
0
0
10
% L
% Met:
0
0
0
0
0
0
10
0
0
0
0
0
0
0
0
% M
% Asn:
10
0
0
0
0
0
0
0
10
0
0
10
10
28
0
% N
% Pro:
10
28
10
37
0
37
10
0
10
46
0
19
10
28
10
% P
% Gln:
0
0
0
0
19
0
19
0
0
0
10
0
28
0
10
% Q
% Arg:
10
0
19
28
19
19
0
19
10
10
0
10
10
0
0
% R
% Ser:
0
10
10
0
10
0
0
19
19
0
10
0
0
10
0
% S
% Thr:
0
10
10
10
10
0
19
0
10
0
0
0
0
0
0
% T
% Val:
19
10
0
0
10
10
0
0
0
0
28
0
0
0
0
% V
% Trp:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
10
10
0
10
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _