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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: MAPK15 All Species: 1.82
Human Site: S403 Identified Species: 4
UniProt: Q8TD08 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8TD08 NP_620590.2 544 59832 S403 H D P A E H E S P R A A K N V
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_539201 559 60934 A410 R Q G A H D E A C G A K N L P
Cat Felis silvestris
Mouse Mus musculus Q80Y86 549 60660 G404 P K P P R S P G H D P E H V E
Rat Rattus norvegicus Q9Z2A6 547 60705 D404 P Q N G H G H D P E H V E V R
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_423954 600 66936 G428 K Q P H T D A G S A A N V Q V
Frog Xenopus laevis P26696 361 41238 L247 L N H I L G I L G S P S Q E D
Zebra Danio Brachydanio rerio NP_001018581 524 58806 G404 K R N Q E S A G V L P A E G A
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_392445 747 85295 T487 N G N L T N L T P S T T K S C
Nematode Worm Caenorhab. elegans Q11179 470 54020 Q356 K A S F K R I Q H E K I R P Y
Sea Urchin Strong. purpuratus XP_001203135 583 64666 A415 G P G G A A A A P Q A P T S T
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P14681 368 42674 K254 F E D F N Q I K S K R A K E Y
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. N.A. 71.5 N.A. 69.2 68.7 N.A. N.A. 45.3 28.6 48.3 N.A. N.A. 34.6 42.6 44.9
Protein Similarity: 100 N.A. N.A. 77.8 N.A. 75.5 75.1 N.A. N.A. 60 42 64.8 N.A. N.A. 50.5 61.2 62.6
P-Site Identity: 100 N.A. N.A. 20 N.A. 6.6 6.6 N.A. N.A. 20 0 13.3 N.A. N.A. 13.3 0 13.3
P-Site Similarity: 100 N.A. N.A. 26.6 N.A. 6.6 13.3 N.A. N.A. 20 20 20 N.A. N.A. 40 13.3 33.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. 29.7 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 42.8 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 13.3 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 26.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 10 0 19 10 10 28 19 0 10 37 28 0 0 10 % A
% Cys: 0 0 0 0 0 0 0 0 10 0 0 0 0 0 10 % C
% Asp: 0 10 10 0 0 19 0 10 0 10 0 0 0 0 10 % D
% Glu: 0 10 0 0 19 0 19 0 0 19 0 10 19 19 10 % E
% Phe: 10 0 0 19 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 10 10 19 19 0 19 0 28 10 10 0 0 0 10 0 % G
% His: 10 0 10 10 19 10 10 0 19 0 10 0 10 0 0 % H
% Ile: 0 0 0 10 0 0 28 0 0 0 0 10 0 0 0 % I
% Lys: 28 10 0 0 10 0 0 10 0 10 10 10 28 0 0 % K
% Leu: 10 0 0 10 10 0 10 10 0 10 0 0 0 10 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 10 10 28 0 10 10 0 0 0 0 0 10 10 10 0 % N
% Pro: 19 10 28 10 0 0 10 0 37 0 28 10 0 10 10 % P
% Gln: 0 28 0 10 0 10 0 10 0 10 0 0 10 10 0 % Q
% Arg: 10 10 0 0 10 10 0 0 0 10 10 0 10 0 10 % R
% Ser: 0 0 10 0 0 19 0 10 19 19 0 10 0 19 0 % S
% Thr: 0 0 0 0 19 0 0 10 0 0 10 10 10 0 10 % T
% Val: 0 0 0 0 0 0 0 0 10 0 0 10 10 19 19 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 19 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _