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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: MAPK15 All Species: 21.82
Human Site: T264 Identified Species: 48
UniProt: Q8TD08 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8TD08 NP_620590.2 544 59832 T264 L G S R P R Q T L D A L L P P
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_539201 559 60934 T265 L G A R P R H T L D T L L P P
Cat Felis silvestris
Mouse Mus musculus Q80Y86 549 60660 T265 L G S R P Q Q T L D A L L P P
Rat Rattus norvegicus Q9Z2A6 547 60705 T265 L G S R P R Q T L D A L L P P
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_423954 600 66936 T289 M S S R Q R V T L E E I L P S
Frog Xenopus laevis P26696 361 41238 L118 M E T D L Y K L L K T Q H L S
Zebra Danio Brachydanio rerio NP_001018581 524 58806 P265 M L L R P Q V P L D E I L P A
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_392445 747 85295 S276 T P N A P R R S L K E L L P E
Nematode Worm Caenorhab. elegans Q11179 470 54020 I227 L F P G S S T I N Q I E R I M
Sea Urchin Strong. purpuratus XP_001203135 583 64666 S266 S K L R H R Q S I E E V L P G
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P14681 368 42674 Y125 D H V Q Y F T Y Q I L R A L K
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. N.A. 71.5 N.A. 69.2 68.7 N.A. N.A. 45.3 28.6 48.3 N.A. N.A. 34.6 42.6 44.9
Protein Similarity: 100 N.A. N.A. 77.8 N.A. 75.5 75.1 N.A. N.A. 60 42 64.8 N.A. N.A. 50.5 61.2 62.6
P-Site Identity: 100 N.A. N.A. 80 N.A. 93.3 100 N.A. N.A. 46.6 6.6 40 N.A. N.A. 40 6.6 33.3
P-Site Similarity: 100 N.A. N.A. 86.6 N.A. 100 100 N.A. N.A. 66.6 26.6 60 N.A. N.A. 60 6.6 60
Percent
Protein Identity: N.A. N.A. N.A. N.A. 29.7 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 42.8 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 0 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 6.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 10 10 0 0 0 0 0 0 28 0 10 0 10 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 10 0 0 10 0 0 0 0 0 46 0 0 0 0 0 % D
% Glu: 0 10 0 0 0 0 0 0 0 19 37 10 0 0 10 % E
% Phe: 0 10 0 0 0 10 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 37 0 10 0 0 0 0 0 0 0 0 0 0 10 % G
% His: 0 10 0 0 10 0 10 0 0 0 0 0 10 0 0 % H
% Ile: 0 0 0 0 0 0 0 10 10 10 10 19 0 10 0 % I
% Lys: 0 10 0 0 0 0 10 0 0 19 0 0 0 0 10 % K
% Leu: 46 10 19 0 10 0 0 10 73 0 10 46 73 19 0 % L
% Met: 28 0 0 0 0 0 0 0 0 0 0 0 0 0 10 % M
% Asn: 0 0 10 0 0 0 0 0 10 0 0 0 0 0 0 % N
% Pro: 0 10 10 0 55 0 0 10 0 0 0 0 0 73 37 % P
% Gln: 0 0 0 10 10 19 37 0 10 10 0 10 0 0 0 % Q
% Arg: 0 0 0 64 0 55 10 0 0 0 0 10 10 0 0 % R
% Ser: 10 10 37 0 10 10 0 19 0 0 0 0 0 0 19 % S
% Thr: 10 0 10 0 0 0 19 46 0 0 19 0 0 0 0 % T
% Val: 0 0 10 0 0 0 19 0 0 0 0 10 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 10 10 0 10 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _