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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MIPOL1
All Species:
12.12
Human Site:
T259
Identified Species:
29.63
UniProt:
Q8TD10
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8TD10
NP_620059.1
442
51537
T259
K
E
C
K
M
R
I
T
A
E
E
M
S
A
L
Chimpanzee
Pan troglodytes
P61584
1003
117506
K626
E
E
E
Y
K
L
E
K
E
E
E
I
S
N
L
Rhesus Macaque
Macaca mulatta
XP_001091057
442
51467
T259
K
E
C
K
M
R
I
T
A
E
E
M
S
A
I
Dog
Lupus familis
XP_537416
430
49790
T260
I
V
D
R
I
Y
K
T
K
E
C
K
K
R
I
Cat
Felis silvestris
Mouse
Mus musculus
Q9D9F8
279
31733
Q109
L
K
L
K
L
E
L
Q
E
K
A
A
E
A
D
Rat
Rattus norvegicus
XP_001079427
378
43428
T208
I
V
D
R
I
Y
K
T
K
E
C
K
K
R
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_421248
408
46760
T238
I
L
N
R
I
H
R
T
K
E
R
K
K
K
I
Frog
Xenopus laevis
Q6GQ73
719
83201
S261
E
T
F
R
L
E
A
S
K
D
D
Y
R
I
R
Zebra Danio
Brachydanio rerio
P13104
284
32704
E114
A
T
A
L
Q
K
L
E
E
A
E
K
A
A
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001184032
785
87890
T602
I
I
G
R
I
S
K
T
K
G
R
R
E
E
I
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
20.2
94.3
78.9
N.A.
41.4
63.7
N.A.
N.A.
51.1
21
22.1
N.A.
N.A.
N.A.
N.A.
21.2
Protein Similarity:
100
32.5
97.2
87
N.A.
52.2
74.4
N.A.
N.A.
66.5
38.7
43.2
N.A.
N.A.
N.A.
N.A.
35.8
P-Site Identity:
100
33.3
93.3
13.3
N.A.
13.3
13.3
N.A.
N.A.
13.3
0
13.3
N.A.
N.A.
N.A.
N.A.
6.6
P-Site Similarity:
100
46.6
100
33.3
N.A.
40
33.3
N.A.
N.A.
33.3
40
33.3
N.A.
N.A.
N.A.
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
0
10
0
0
0
10
0
20
10
10
10
10
40
0
% A
% Cys:
0
0
20
0
0
0
0
0
0
0
20
0
0
0
0
% C
% Asp:
0
0
20
0
0
0
0
0
0
10
10
0
0
0
20
% D
% Glu:
20
30
10
0
0
20
10
10
30
60
40
0
20
10
0
% E
% Phe:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
10
0
0
0
0
0
0
10
0
0
0
0
0
% G
% His:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% H
% Ile:
40
10
0
0
40
0
20
0
0
0
0
10
0
10
50
% I
% Lys:
20
10
0
30
10
10
30
10
50
10
0
40
30
10
0
% K
% Leu:
10
10
10
10
20
10
20
0
0
0
0
0
0
0
20
% L
% Met:
0
0
0
0
20
0
0
0
0
0
0
20
0
0
0
% M
% Asn:
0
0
10
0
0
0
0
0
0
0
0
0
0
10
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
10
0
0
10
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
50
0
20
10
0
0
0
20
10
10
20
10
% R
% Ser:
0
0
0
0
0
10
0
10
0
0
0
0
30
0
0
% S
% Thr:
0
20
0
0
0
0
0
60
0
0
0
0
0
0
0
% T
% Val:
0
20
0
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
10
0
20
0
0
0
0
0
10
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _