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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
BICD2
All Species:
21.52
Human Site:
S286
Identified Species:
39.44
UniProt:
Q8TD16
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8TD16
NP_001003800.1
824
93533
S286
S
L
D
G
L
K
F
S
D
D
A
A
E
P
N
Chimpanzee
Pan troglodytes
XP_520695
824
93543
S286
S
L
D
G
L
K
F
S
D
D
A
A
E
P
N
Rhesus Macaque
Macaca mulatta
XP_001103849
824
93513
S286
S
L
D
G
L
K
F
S
D
D
A
A
E
P
N
Dog
Lupus familis
XP_541330
836
94592
G286
S
L
D
G
L
K
L
G
D
D
T
E
A
L
A
Cat
Felis silvestris
Mouse
Mus musculus
Q921C5
820
93372
S286
S
L
D
G
L
K
F
S
D
D
T
V
T
A
E
Rat
Rattus norvegicus
NP_001028846
851
96691
S286
S
L
D
G
L
K
F
S
D
D
A
V
T
A
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508342
737
84371
L253
E
R
E
K
V
N
L
L
S
T
L
Q
E
S
Q
Chicken
Gallus gallus
XP_414332
815
93688
S286
S
L
D
G
L
K
F
S
D
E
A
T
E
P
N
Frog
Xenopus laevis
NP_001089257
656
76176
E172
L
Q
D
F
S
E
L
E
E
E
N
I
S
L
L
Zebra Danio
Brachydanio rerio
XP_685529
809
92084
P286
L
K
L
S
A
D
E
P
N
N
D
D
A
I
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P16568
782
88935
Y274
Y
H
I
S
N
L
A
Y
S
I
R
S
N
M
E
Honey Bee
Apis mellifera
XP_396412
766
87933
S257
E
L
D
Q
R
I
N
S
E
S
I
Y
N
L
S
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_798054
762
88207
N270
A
I
N
V
D
L
E
N
N
S
Q
F
H
Y
M
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.8
98.7
89.5
N.A.
94.9
91.1
N.A.
70
82.6
39.2
67.4
N.A.
39.3
39.8
N.A.
39.4
Protein Similarity:
100
99.8
99
92.1
N.A.
96.5
93.1
N.A.
79
91.1
56.6
80.3
N.A.
59
58.7
N.A.
60.1
P-Site Identity:
100
100
100
53.3
N.A.
66.6
73.3
N.A.
6.6
86.6
6.6
0
N.A.
0
20
N.A.
0
P-Site Similarity:
100
100
100
53.3
N.A.
66.6
73.3
N.A.
20
93.3
26.6
13.3
N.A.
6.6
33.3
N.A.
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
0
0
8
0
8
0
0
0
39
24
16
16
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
70
0
8
8
0
0
54
47
8
8
0
0
0
% D
% Glu:
16
0
8
0
0
8
16
8
16
16
0
8
39
0
24
% E
% Phe:
0
0
0
8
0
0
47
0
0
0
0
8
0
0
0
% F
% Gly:
0
0
0
54
0
0
0
8
0
0
0
0
0
0
0
% G
% His:
0
8
0
0
0
0
0
0
0
0
0
0
8
0
0
% H
% Ile:
0
8
8
0
0
8
0
0
0
8
8
8
0
8
0
% I
% Lys:
0
8
0
8
0
54
0
0
0
0
0
0
0
0
0
% K
% Leu:
16
62
8
0
54
16
24
8
0
0
8
0
0
24
16
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
8
% M
% Asn:
0
0
8
0
8
8
8
8
16
8
8
0
16
0
31
% N
% Pro:
0
0
0
0
0
0
0
8
0
0
0
0
0
31
0
% P
% Gln:
0
8
0
8
0
0
0
0
0
0
8
8
0
0
8
% Q
% Arg:
0
8
0
0
8
0
0
0
0
0
8
0
0
0
0
% R
% Ser:
54
0
0
16
8
0
0
54
16
16
0
8
8
8
8
% S
% Thr:
0
0
0
0
0
0
0
0
0
8
16
8
16
0
0
% T
% Val:
0
0
0
8
8
0
0
0
0
0
0
16
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
8
0
0
0
0
0
0
8
0
0
0
8
0
8
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _