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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
BICD2
All Species:
31.82
Human Site:
S418
Identified Species:
58.33
UniProt:
Q8TD16
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8TD16
NP_001003800.1
824
93533
S418
D
N
E
K
D
R
D
S
H
E
D
G
D
Y
Y
Chimpanzee
Pan troglodytes
XP_520695
824
93543
S418
D
N
E
K
D
R
D
S
H
E
D
G
D
Y
Y
Rhesus Macaque
Macaca mulatta
XP_001103849
824
93513
S418
D
N
E
K
D
R
D
S
H
E
D
G
D
Y
Y
Dog
Lupus familis
XP_541330
836
94592
S411
D
S
E
K
E
R
D
S
H
E
D
G
D
Y
Y
Cat
Felis silvestris
Mouse
Mus musculus
Q921C5
820
93372
S420
D
N
E
K
D
R
D
S
H
E
D
G
D
Y
Y
Rat
Rattus norvegicus
NP_001028846
851
96691
S420
D
N
E
K
D
R
D
S
H
E
D
G
D
Y
Y
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508342
737
84371
G362
S
K
Y
E
A
E
K
G
R
Y
E
T
D
S
Q
Chicken
Gallus gallus
XP_414332
815
93688
S417
D
N
E
K
D
R
D
S
H
E
D
G
D
Y
Y
Frog
Xenopus laevis
NP_001089257
656
76176
S281
S
G
Y
N
F
G
I
S
K
T
N
G
E
I
L
Zebra Danio
Brachydanio rerio
XP_685529
809
92084
S413
D
S
E
R
E
R
D
S
R
E
D
N
D
V
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P16568
782
88935
K383
V
D
A
L
V
Q
L
K
K
Q
I
D
V
K
E
Honey Bee
Apis mellifera
XP_396412
766
87933
A369
A
R
I
V
Q
L
A
A
H
V
Q
S
L
H
H
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_798054
762
88207
H379
P
T
E
G
E
I
D
H
S
Q
Y
Q
H
L
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.8
98.7
89.5
N.A.
94.9
91.1
N.A.
70
82.6
39.2
67.4
N.A.
39.3
39.8
N.A.
39.4
Protein Similarity:
100
99.8
99
92.1
N.A.
96.5
93.1
N.A.
79
91.1
56.6
80.3
N.A.
59
58.7
N.A.
60.1
P-Site Identity:
100
100
100
86.6
N.A.
100
100
N.A.
6.6
100
13.3
53.3
N.A.
0
6.6
N.A.
13.3
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
20
100
26.6
73.3
N.A.
20
26.6
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
8
0
8
0
8
8
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
62
8
0
0
47
0
70
0
0
0
62
8
70
0
16
% D
% Glu:
0
0
70
8
24
8
0
0
0
62
8
0
8
0
8
% E
% Phe:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
8
0
8
0
8
0
8
0
0
0
62
0
0
0
% G
% His:
0
0
0
0
0
0
0
8
62
0
0
0
8
8
8
% H
% Ile:
0
0
8
0
0
8
8
0
0
0
8
0
0
8
0
% I
% Lys:
0
8
0
54
0
0
8
8
16
0
0
0
0
8
0
% K
% Leu:
0
0
0
8
0
8
8
0
0
0
0
0
8
8
8
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
47
0
8
0
0
0
0
0
0
8
8
0
0
0
% N
% Pro:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
8
8
0
0
0
16
8
8
0
0
8
% Q
% Arg:
0
8
0
8
0
62
0
0
16
0
0
0
0
0
0
% R
% Ser:
16
16
0
0
0
0
0
70
8
0
0
8
0
8
0
% S
% Thr:
0
8
0
0
0
0
0
0
0
8
0
8
0
0
0
% T
% Val:
8
0
0
8
8
0
0
0
0
8
0
0
8
8
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
16
0
0
0
0
0
0
8
8
0
0
54
54
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _