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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
BICD2
All Species:
23.64
Human Site:
S486
Identified Species:
43.33
UniProt:
Q8TD16
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8TD16
NP_001003800.1
824
93533
S486
Q
A
L
T
E
K
V
S
L
L
E
K
A
S
R
Chimpanzee
Pan troglodytes
XP_520695
824
93543
S486
Q
A
L
T
E
K
V
S
L
L
E
K
A
S
R
Rhesus Macaque
Macaca mulatta
XP_001103849
824
93513
S486
Q
A
L
M
E
K
V
S
L
L
E
K
A
S
R
Dog
Lupus familis
XP_541330
836
94592
S479
Q
A
L
T
E
K
V
S
L
L
E
K
A
S
R
Cat
Felis silvestris
Mouse
Mus musculus
Q921C5
820
93372
S488
Q
A
L
T
E
K
I
S
L
L
E
K
A
S
H
Rat
Rattus norvegicus
NP_001028846
851
96691
S488
Q
A
L
T
E
K
V
S
L
L
E
K
A
S
H
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508342
737
84371
N426
T
F
S
E
E
L
A
N
L
Y
H
H
V
C
M
Chicken
Gallus gallus
XP_414332
815
93688
A485
Q
A
L
T
E
K
I
A
S
L
E
K
S
S
R
Frog
Xenopus laevis
NP_001089257
656
76176
L345
L
E
E
L
K
N
N
L
D
V
T
K
E
A
L
Zebra Danio
Brachydanio rerio
XP_685529
809
92084
D477
R
L
E
G
H
V
R
D
L
S
I
Q
V
S
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P16568
782
88935
L447
Y
T
D
A
T
T
T
L
R
N
E
V
T
N
L
Honey Bee
Apis mellifera
XP_396412
766
87933
Q433
L
T
I
S
D
S
T
Q
Q
L
R
T
E
L
T
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_798054
762
88207
T444
Q
K
E
V
Q
L
M
T
D
R
N
R
K
Q
Q
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.8
98.7
89.5
N.A.
94.9
91.1
N.A.
70
82.6
39.2
67.4
N.A.
39.3
39.8
N.A.
39.4
Protein Similarity:
100
99.8
99
92.1
N.A.
96.5
93.1
N.A.
79
91.1
56.6
80.3
N.A.
59
58.7
N.A.
60.1
P-Site Identity:
100
100
93.3
100
N.A.
86.6
93.3
N.A.
13.3
73.3
6.6
13.3
N.A.
6.6
6.6
N.A.
6.6
P-Site Similarity:
100
100
93.3
100
N.A.
93.3
93.3
N.A.
20
93.3
26.6
33.3
N.A.
13.3
26.6
N.A.
40
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
54
0
8
0
0
8
8
0
0
0
0
47
8
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% C
% Asp:
0
0
8
0
8
0
0
8
16
0
0
0
0
0
0
% D
% Glu:
0
8
24
8
62
0
0
0
0
0
62
0
16
0
0
% E
% Phe:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
8
0
0
0
0
0
8
8
0
0
16
% H
% Ile:
0
0
8
0
0
0
16
0
0
0
8
0
0
0
0
% I
% Lys:
0
8
0
0
8
54
0
0
0
0
0
62
8
0
0
% K
% Leu:
16
8
54
8
0
16
0
16
62
62
0
0
0
8
16
% L
% Met:
0
0
0
8
0
0
8
0
0
0
0
0
0
0
8
% M
% Asn:
0
0
0
0
0
8
8
8
0
8
8
0
0
8
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
62
0
0
0
8
0
0
8
8
0
0
8
0
8
16
% Q
% Arg:
8
0
0
0
0
0
8
0
8
8
8
8
0
0
39
% R
% Ser:
0
0
8
8
0
8
0
47
8
8
0
0
8
62
0
% S
% Thr:
8
16
0
47
8
8
16
8
0
0
8
8
8
0
8
% T
% Val:
0
0
0
8
0
8
39
0
0
8
0
8
16
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
8
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _