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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: BICD2 All Species: 11.52
Human Site: S605 Identified Species: 21.11
UniProt: Q8TD16 Number Species: 12
    Phosphosite Substitution
    Charge Score: -0.17
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8TD16 NP_001003800.1 824 93533 S605 A D G G T G D S S P S P G S S
Chimpanzee Pan troglodytes XP_520695 824 93543 S605 A D G G T G D S S P S P G S S
Rhesus Macaque Macaca mulatta XP_001103849 824 93513 S605 A D G G S G D S S P S P G S S
Dog Lupus familis XP_541330 836 94592 S593 S S P S P S P S L P S P L S D
Cat Felis silvestris
Mouse Mus musculus Q921C5 820 93372 P605 T G D N S P S P S S S L P S P
Rat Rattus norvegicus NP_001028846 851 96691 P605 T G D N S P S P S S S L P S P
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001508342 737 84371 Q537 R T T E L S R Q R V A S Q E L
Chicken Gallus gallus XP_414332 815 93688 P600 S G D S S P S P V S S L P S P
Frog Xenopus laevis NP_001089257 656 76176 L456 L D E L Q E D L K T L R R S Y
Zebra Danio Brachydanio rerio XP_685529 809 92084 R591 S N S I P V D R E E P R P E P
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P16568 782 88935 L559 I V E D L Q G L A D S V E I K
Honey Bee Apis mellifera XP_396412 766 87933 K545 K D L E S L S K A K E I A K H
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_798054 762 88207 S555 G A A S P S G S P S K R S N E
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.8 98.7 89.5 N.A. 94.9 91.1 N.A. 70 82.6 39.2 67.4 N.A. 39.3 39.8 N.A. 39.4
Protein Similarity: 100 99.8 99 92.1 N.A. 96.5 93.1 N.A. 79 91.1 56.6 80.3 N.A. 59 58.7 N.A. 60.1
P-Site Identity: 100 100 93.3 33.3 N.A. 20 20 N.A. 0 13.3 20 6.6 N.A. 6.6 6.6 N.A. 6.6
P-Site Similarity: 100 100 100 40 N.A. 26.6 26.6 N.A. 6.6 26.6 20 20 N.A. 13.3 20 N.A. 13.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 24 8 8 0 0 0 0 0 16 0 8 0 8 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 39 24 8 0 0 39 0 0 8 0 0 0 0 8 % D
% Glu: 0 0 16 16 0 8 0 0 8 8 8 0 8 16 8 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 8 24 24 24 0 24 16 0 0 0 0 0 24 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8 % H
% Ile: 8 0 0 8 0 0 0 0 0 0 0 8 0 8 0 % I
% Lys: 8 0 0 0 0 0 0 8 8 8 8 0 0 8 8 % K
% Leu: 8 0 8 8 16 8 0 16 8 0 8 24 8 0 8 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 8 0 16 0 0 0 0 0 0 0 0 0 8 0 % N
% Pro: 0 0 8 0 24 24 8 24 8 31 8 31 31 0 31 % P
% Gln: 0 0 0 0 8 8 0 8 0 0 0 0 8 0 0 % Q
% Arg: 8 0 0 0 0 0 8 8 8 0 0 24 8 0 0 % R
% Ser: 24 8 8 24 39 24 31 39 39 31 62 8 8 62 24 % S
% Thr: 16 8 8 0 16 0 0 0 0 8 0 0 0 0 0 % T
% Val: 0 8 0 0 0 8 0 0 8 8 0 8 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _