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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: BICD2 All Species: 15.45
Human Site: S608 Identified Species: 28.33
UniProt: Q8TD16 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8TD16 NP_001003800.1 824 93533 S608 G T G D S S P S P G S S L P S
Chimpanzee Pan troglodytes XP_520695 824 93543 S608 G T G D S S P S P G S S L P S
Rhesus Macaque Macaca mulatta XP_001103849 824 93513 S608 G S G D S S P S P G S S L P S
Dog Lupus familis XP_541330 836 94592 S596 S P S P S L P S P L S D P R R
Cat Felis silvestris
Mouse Mus musculus Q921C5 820 93372 S608 N S P S P S S S L P S P L S D
Rat Rattus norvegicus NP_001028846 851 96691 S608 N S P S P S S S L P S P L S D
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001508342 737 84371 A540 E L S R Q R V A S Q E L G P V
Chicken Gallus gallus XP_414332 815 93688 S603 S S P S P V S S L P S P V S D
Frog Xenopus laevis NP_001089257 656 76176 L459 L Q E D L K T L R R S Y C D V
Zebra Danio Brachydanio rerio XP_685529 809 92084 P594 I P V D R E E P R P E P M D V
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P16568 782 88935 S562 D L Q G L A D S V E I K K Y V
Honey Bee Apis mellifera XP_396412 766 87933 E548 E S L S K A K E I A K H I E T
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_798054 762 88207 K558 S P S G S P S K R S N E H A K
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.8 98.7 89.5 N.A. 94.9 91.1 N.A. 70 82.6 39.2 67.4 N.A. 39.3 39.8 N.A. 39.4
Protein Similarity: 100 99.8 99 92.1 N.A. 96.5 93.1 N.A. 79 91.1 56.6 80.3 N.A. 59 58.7 N.A. 60.1
P-Site Identity: 100 100 93.3 33.3 N.A. 26.6 26.6 N.A. 6.6 13.3 13.3 6.6 N.A. 6.6 0 N.A. 6.6
P-Site Similarity: 100 100 100 33.3 N.A. 33.3 33.3 N.A. 13.3 26.6 13.3 13.3 N.A. 13.3 26.6 N.A. 13.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 16 0 8 0 8 0 0 0 8 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 8 0 0 % C
% Asp: 8 0 0 39 0 0 8 0 0 0 0 8 0 16 24 % D
% Glu: 16 0 8 0 0 8 8 8 0 8 16 8 0 8 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 24 0 24 16 0 0 0 0 0 24 0 0 8 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 8 8 0 0 % H
% Ile: 8 0 0 0 0 0 0 0 8 0 8 0 8 0 0 % I
% Lys: 0 0 0 0 8 8 8 8 0 0 8 8 8 0 8 % K
% Leu: 8 16 8 0 16 8 0 8 24 8 0 8 39 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 8 0 0 % M
% Asn: 16 0 0 0 0 0 0 0 0 0 8 0 0 0 0 % N
% Pro: 0 24 24 8 24 8 31 8 31 31 0 31 8 31 0 % P
% Gln: 0 8 8 0 8 0 0 0 0 8 0 0 0 0 0 % Q
% Arg: 0 0 0 8 8 8 0 0 24 8 0 0 0 8 8 % R
% Ser: 24 39 24 31 39 39 31 62 8 8 62 24 0 24 24 % S
% Thr: 0 16 0 0 0 0 8 0 0 0 0 0 0 0 8 % T
% Val: 0 0 8 0 0 8 8 0 8 0 0 0 8 0 31 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 8 0 8 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _