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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
BICD2
All Species:
9.09
Human Site:
S618
Identified Species:
16.67
UniProt:
Q8TD16
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.33
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8TD16
NP_001003800.1
824
93533
S618
S
S
L
P
S
P
L
S
D
P
R
R
E
P
M
Chimpanzee
Pan troglodytes
XP_520695
824
93543
S618
S
S
L
P
S
P
L
S
D
P
R
R
E
P
M
Rhesus Macaque
Macaca mulatta
XP_001103849
824
93513
S618
S
S
L
P
S
P
L
S
D
P
R
R
E
P
M
Dog
Lupus familis
XP_541330
836
94592
M606
S
D
P
R
R
E
P
M
N
I
Y
N
L
I
A
Cat
Felis silvestris
Mouse
Mus musculus
Q921C5
820
93372
R618
S
P
L
S
D
P
R
R
E
P
M
N
I
Y
N
Rat
Rattus norvegicus
NP_001028846
851
96691
R618
S
P
L
S
D
P
R
R
E
P
M
N
I
Y
N
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508342
737
84371
K550
E
L
G
P
V
V
D
K
D
K
E
A
L
M
E
Chicken
Gallus gallus
XP_414332
815
93688
K613
S
P
V
S
D
P
R
K
E
P
M
N
I
Y
N
Frog
Xenopus laevis
NP_001089257
656
76176
K469
S
Y
C
D
V
Q
S
K
L
N
L
A
Q
D
E
Zebra Danio
Brachydanio rerio
XP_685529
809
92084
L604
E
P
M
D
V
Y
N
L
V
A
I
I
R
D
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P16568
782
88935
V572
I
K
K
Y
V
D
T
V
S
D
Q
I
K
Y
L
Honey Bee
Apis mellifera
XP_396412
766
87933
D558
K
H
I
E
T
A
I
D
Q
I
K
H
L
R
S
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_798054
762
88207
G568
N
E
H
A
K
F
N
G
D
T
V
T
C
T
T
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.8
98.7
89.5
N.A.
94.9
91.1
N.A.
70
82.6
39.2
67.4
N.A.
39.3
39.8
N.A.
39.4
Protein Similarity:
100
99.8
99
92.1
N.A.
96.5
93.1
N.A.
79
91.1
56.6
80.3
N.A.
59
58.7
N.A.
60.1
P-Site Identity:
100
100
100
6.6
N.A.
26.6
26.6
N.A.
13.3
20
6.6
0
N.A.
0
0
N.A.
6.6
P-Site Similarity:
100
100
100
13.3
N.A.
33.3
33.3
N.A.
13.3
33.3
13.3
6.6
N.A.
20
26.6
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
8
0
8
0
0
0
8
0
16
0
0
8
% A
% Cys:
0
0
8
0
0
0
0
0
0
0
0
0
8
0
0
% C
% Asp:
0
8
0
16
24
8
8
8
39
8
0
0
0
16
0
% D
% Glu:
16
8
0
8
0
8
0
0
24
0
8
0
24
0
16
% E
% Phe:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
8
0
0
0
0
8
0
0
0
0
0
0
0
% G
% His:
0
8
8
0
0
0
0
0
0
0
0
8
0
0
0
% H
% Ile:
8
0
8
0
0
0
8
0
0
16
8
16
24
8
0
% I
% Lys:
8
8
8
0
8
0
0
24
0
8
8
0
8
0
0
% K
% Leu:
0
8
39
0
0
0
24
8
8
0
8
0
24
0
8
% L
% Met:
0
0
8
0
0
0
0
8
0
0
24
0
0
8
24
% M
% Asn:
8
0
0
0
0
0
16
0
8
8
0
31
0
0
24
% N
% Pro:
0
31
8
31
0
47
8
0
0
47
0
0
0
24
0
% P
% Gln:
0
0
0
0
0
8
0
0
8
0
8
0
8
0
8
% Q
% Arg:
0
0
0
8
8
0
24
16
0
0
24
24
8
8
0
% R
% Ser:
62
24
0
24
24
0
8
24
8
0
0
0
0
0
8
% S
% Thr:
0
0
0
0
8
0
8
0
0
8
0
8
0
8
8
% T
% Val:
0
0
8
0
31
8
0
8
8
0
8
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
8
0
8
0
8
0
0
0
0
8
0
0
31
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _